Excess electron transport through DNA: A single electron repairs more than one UV-induced lesion

Bernd Giese; Barbara Carl; Thomas Carl; Thomas Carell; Christoph Behrens; Ulrich Hennecke; Olav Schiemann; Emiliano Feresin

doi:10.1002/anie.200353264

Excess electron transport through DNA: A single electron repairs more than one UV-induced lesion

Bernd Giese, Barbara Carl, Thomas Carl, Thomas Carell, Christoph Behrens, Ulrich Hennecke, Olav Schiemann, Emiliano Feresin

Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

75 Zitate (Scopus)

Abstract

Site-selective injection of a single electron into thymine (yellow) through the modified nucleoside 1 (1→2) was used to examine the dependence of excess electron transfer in DNA on distance. The DNA was cleaved upon arrival of the electron at a thymine dimer (red). This assay showed that one electron can repair more than one UV-induced lesion in DNA 3.

Originalsprache	Englisch
Seiten (von - bis)	1848-1851
Seitenumfang	4
Fachzeitschrift	Angewandte Chemie International Edition in English
Jahrgang	43
Ausgabenummer	14
DOIs	https://doi.org/10.1002/anie.200353264
Publikationsstatus	Veröffentlicht - 26 März 2004
Extern publiziert	Ja

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10.1002/anie.200353264

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abstract = "Site-selective injection of a single electron into thymine (yellow) through the modified nucleoside 1 (1→2) was used to examine the dependence of excess electron transfer in DNA on distance. The DNA was cleaved upon arrival of the electron at a thymine dimer (red). This assay showed that one electron can repair more than one UV-induced lesion in DNA 3.",

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AU - Hennecke, Ulrich

AU - Schiemann, Olav

AU - Feresin, Emiliano

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KW - DNA damage

KW - ESR spectroscopy

KW - Electron transfer

KW - Nucleotides

KW - Radical ions

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Excess electron transport through DNA: A single electron repairs more than one UV-induced lesion

Abstract

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