TY - JOUR
T1 - Event-related potentials and EMDR treatment of post-traumatic stress disorder
AU - Lamprecht, Friedhelm
AU - Köhnke, Christine
AU - Lempa, Wolfgang
AU - Sack, Martin
AU - Matzke, Mike
AU - Münte, Thomas F.
N1 - Funding Information:
We thank J. Kilian and A. Niesel for technical assistance. TFM is supported by the DFG.
PY - 2004/6
Y1 - 2004/6
N2 - Ten patients suffering from post-traumatic stress disorder (PTSD) following a severe traumatic event, were assessed with event-related brain potentials (ERPs) in a modified oddball paradigm containing auditory standard, target, and novel tones. ERPs were assessed before and after a treatment session using the eye movement desensitization and reprocessing method. Compared to a control group that underwent sham treatment, ERPs of the patients showed a reduction of the P3a component in the post-treatment recording, suggesting a reduced orienting to novel stimuli and reduced arousal level after the treatment. Moreover, psychometric assessment revealed a marked improvement of the PTSD symptoms after treatment.
AB - Ten patients suffering from post-traumatic stress disorder (PTSD) following a severe traumatic event, were assessed with event-related brain potentials (ERPs) in a modified oddball paradigm containing auditory standard, target, and novel tones. ERPs were assessed before and after a treatment session using the eye movement desensitization and reprocessing method. Compared to a control group that underwent sham treatment, ERPs of the patients showed a reduction of the P3a component in the post-treatment recording, suggesting a reduced orienting to novel stimuli and reduced arousal level after the treatment. Moreover, psychometric assessment revealed a marked improvement of the PTSD symptoms after treatment.
KW - Event-related potential
KW - Eye movement desensitization
KW - P3
KW - PTSD
UR - http://www.scopus.com/inward/record.url?scp=2342509531&partnerID=8YFLogxK
U2 - 10.1016/j.neures.2004.02.013
DO - 10.1016/j.neures.2004.02.013
M3 - Article
C2 - 15140569
AN - SCOPUS:2342509531
SN - 0168-0102
VL - 49
SP - 267
EP - 272
JO - Neuroscience Research
JF - Neuroscience Research
IS - 2
ER -