E-Cadherin Gene Mutations Provide Clues to Diffuse Type Gastric Carcinomas

Keyphrases

• Gene mutation 100%
• E-cadherin 100%
• E-cadherin Gene 100%
• Diffuse-type Gastric Carcinoma 100%
• Tumor 75%
• Gastric Carcinoma 75%
• Diffuse Type 75%
• Splicing mutation 50%
• E-cadherin mutations 50%
• Exon 9 50%
• Intestinal Type 50%
• Mixed Carcinoma 50%
• Cell-cell Communication 25%
• Quantitative PCR 25%
• Direct Sequencing 25%
• Point mutation 25%
• Protein Level 25%
• MRNA Level 25%
• Amino Acid Sequence 25%
• Exon 25%
• Splice Site 25%
• Exon Deletion 25%
• Complementary DNA (cDNA) 25%
• Somatic mutation 25%
• Binding Region 25%
• Two-point 25%
• Protein-DNA Complex 25%
• Lymph Node Metastasis 25%
• Tumor-node-metastasis 25%
• Carcinoma 25%
• DNA Fragments 25%
• Epithelial Tissue 25%
• In Vivo Evidence 25%
• Exon 10 25%
• Alternative Splicing 25%
• Cell Adhesion Molecules 25%
• Immunoreactivity 25%
• Loss of Heterozygosity 25%
• Calcium-dependent 25%
• Suppressor Genes 25%
• Immunohistochemical Evaluation 25%
• Frame Skipping 25%
• Splicing Mechanism 25%
• Tumor Metastasis Suppressor 25%
• Gastric Tissue 25%
• Epithelial Cadherin 25%
• Calcium Binding 25%
• Calcium-binding Domain 25%
• Metastasis Suppressor 25%
• Exon 8 25%

Biochemistry, Genetics and Molecular Biology

• Gene Mutation 100%
• Cadherin 100%
• Exon 54%
• Splice Site Mutation 18%
• Calcium Binding 18%
• Suppressor Gene 18%
• Peptide Sequence 9%
• Binding Domain 9%
• Cell-Cell Interaction 9%
• Complementary DNA 9%
• Loss of Heterozygosity 9%
• Cell Adhesion Proteins 9%
• Somatic Mutation 9%
• Allele 9%
• Alternative Splicing 9%
• Point Mutation 9%
• DNA RNA Hybridization 9%
• Immunoreactivity 9%
• Metastasis Suppressor 9%
• Messenger RNA 9%
• Reverse Transcription Polymerase Chain Reaction 9%