@article{e0c6bcc2a1d344dfbb74ba3b0ac27112,
title = "Downbeat nystagmus caused by a paramedian ponto-medullary lesion",
abstract = "Downbeat nystagmus (DBN) is rarely caused by lesions in sites other than the cerebellar (para-)floccular lobe. We describe a case of DBN secondary to a hemorrhaged venous cavernoma at the pontomedullary junction. This case provides new insights into the neuro-anatomical substrate of DBN. We propose that DBN arises from lesions in a brainstem-cerebellar feedback loop, which comprises cells of the pontine paramedian tract (PMT).",
keywords = "Downbeat nystagmus, Flocculus, Paramedian tract",
author = "Judith Wagner and Nadine Lehnen and Stefan Glasauer and Nicole Rettinger and Ulrich B{\"u}ttner and Thomas Brandt and Michael Strupp",
note = "Funding Information: Supported by Deutsche Forschungsgemeinschaft Gl 342/1-3. We thank Thomas Eggert for maintenance of the coil system. This study was conducted according to the ethical principles laid down in the 1964 Declaration of Helsinki and was approved by the local ethics committee. The patient described in this manuscript gave his informed consent prior to inclusion in the study.",
year = "2009",
month = sep,
doi = "10.1007/s00415-009-5153-z",
language = "English",
volume = "256",
pages = "1572--1574",
journal = "Journal of Neurology",
issn = "0340-5354",
number = "9",
}