Die bilirubinbestimmung - Eine aktuelle übersicht

The goal of precise, accurate and specific measurement of bilirubin and its subfractions in serum has not yet been achieved, despite many different methods being available. In addition to the traditional photometric diazo procedures, drychemistry methods, direct spectrophotometry in serum and whole blood and for scientific purposes separations by HPLC were established. For point-of-care diagnostics several test procedures are available. This article reviews the most notable methods and describes advantages and disadvantages of the different bilirubin analyses.