Deuteration of Hyperpolarized 13C-Labeled Zymonic Acid Enables Sensitivity-Enhanced Dynamic MRI of pH

Christian Hundshammer; Stephan Düwel; Simone S. Köcher; Malte Gersch; Benedikt Feuerecker; Christoph Scheurer; Axel Haase; Steffen J. Glaser; Markus Schwaiger; Franz Schilling

doi:10.1002/cphc.201700956

Deuteration of Hyperpolarized ¹³C-Labeled Zymonic Acid Enables Sensitivity-Enhanced Dynamic MRI of pH

Christian Hundshammer, Stephan Düwel, Simone S. Köcher, Malte Gersch, Benedikt Feuerecker, Christoph Scheurer, Axel Haase, Steffen J. Glaser, Markus Schwaiger, Franz Schilling

Professur für Organische Chemie

Publikation: Beitrag in Fachzeitschrift › Kommentar/Debatte

Abstract

The front cover artwork is provided by the groups of Dr. Christoph Scheurer, Prof. Axel Haase, Prof. Steffen J. Glaser, Prof. Markus Schwaiger and Dr. Franz Schilling from Technical University of Munich. The image shows deuterated zymonic acid, its pH-sensitive ¹³C NMR resonances and examples of how this sensor can be used to non-invasively image pH both in vitro and in vivo. Read the full text of the article at 10.1002/cphc.201700779.

Originalsprache	Englisch
Seiten (von - bis)	2421
Seitenumfang	1
Fachzeitschrift	ChemPhysChem
Jahrgang	18
Ausgabenummer	18
DOIs	https://doi.org/10.1002/cphc.201700956
Publikationsstatus	Veröffentlicht - 20 Sept. 2017

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10.1002/cphc.201700956

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AU - Hundshammer, Christian

AU - Düwel, Stephan

AU - Köcher, Simone S.

AU - Gersch, Malte

AU - Feuerecker, Benedikt

AU - Scheurer, Christoph

AU - Haase, Axel

AU - Glaser, Steffen J.

AU - Schwaiger, Markus

AU - Schilling, Franz

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