Cytokines of the IL-17 family in psoriasis

Felix Lauffer; Kilian Eyerich; Wolf Henning Boehncke; Khusru Asadullah; Stefan Beissert; Kamran Ghoreschi; Michael P. Schön

doi:10.1111/ddg.14124

Cytokines of the IL-17 family in psoriasis

Felix Lauffer, Kilian Eyerich, Wolf Henning Boehncke, Khusru Asadullah, Stefan Beissert, Kamran Ghoreschi, Michael P. Schön

Publikation: Beitrag in Fachzeitschrift › Übersichtsartikel › Begutachtung

32 Zitate (Scopus)

Abstract

Various immune cells and their messenger substances influence the development of psoriasis. Cytokines of the IL-17 family are of particular importance. In addition to IL-17A, which plays a central role in the pathogenesis of psoriasis, other subtypes of the IL-17 family also have a proinflammatory effect. This review provides an up-to-date overview of the immunopathogenesis of psoriasis with regard to the six IL-17 subtypes, in particular their physiological and pathogenic properties, as well as their significance for psoriasis therapy.

Originalsprache	Englisch
Seiten (von - bis)	675-681
Seitenumfang	7
Fachzeitschrift	JDDG - Journal of the German Society of Dermatology
Jahrgang	18
Ausgabenummer	7
DOIs	https://doi.org/10.1111/ddg.14124
Publikationsstatus	Veröffentlicht - 1 Juli 2020
Extern publiziert	Ja

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10.1111/ddg.14124

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title = "Cytokines of the IL-17 family in psoriasis",

abstract = "Various immune cells and their messenger substances influence the development of psoriasis. Cytokines of the IL-17 family are of particular importance. In addition to IL-17A, which plays a central role in the pathogenesis of psoriasis, other subtypes of the IL-17 family also have a proinflammatory effect. This review provides an up-to-date overview of the immunopathogenesis of psoriasis with regard to the six IL-17 subtypes, in particular their physiological and pathogenic properties, as well as their significance for psoriasis therapy.",

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AU - Lauffer, Felix

AU - Eyerich, Kilian

AU - Boehncke, Wolf Henning

AU - Asadullah, Khusru

AU - Beissert, Stefan

AU - Ghoreschi, Kamran

AU - Schön, Michael P.

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N2 - Various immune cells and their messenger substances influence the development of psoriasis. Cytokines of the IL-17 family are of particular importance. In addition to IL-17A, which plays a central role in the pathogenesis of psoriasis, other subtypes of the IL-17 family also have a proinflammatory effect. This review provides an up-to-date overview of the immunopathogenesis of psoriasis with regard to the six IL-17 subtypes, in particular their physiological and pathogenic properties, as well as their significance for psoriasis therapy.

AB - Various immune cells and their messenger substances influence the development of psoriasis. Cytokines of the IL-17 family are of particular importance. In addition to IL-17A, which plays a central role in the pathogenesis of psoriasis, other subtypes of the IL-17 family also have a proinflammatory effect. This review provides an up-to-date overview of the immunopathogenesis of psoriasis with regard to the six IL-17 subtypes, in particular their physiological and pathogenic properties, as well as their significance for psoriasis therapy.

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Cytokines of the IL-17 family in psoriasis

Abstract

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