CreER^T2 expression from within the c-Kit gene locus allows efficient inducible gene targeting in and ablation of mast cells

Keyphrases

• Ablation 100%
• Gene Locus 100%
• Mast Cells 100%
• Gene Targeting 100%
• Inducible Genes 100%
• KIT Gene 100%
• CreERT2 100%
• Cellular Homeostasis 33%
• Gene Expression 16%
• Immune Response 16%
• Knock-in Mouse Model 16%
• Innate Immune Response 16%
• Adaptive Immune Response 16%
• Hematopoietic Cells 16%
• Anatomical Location 16%
• Cell Function 16%
• Cell Development 16%
• Cre Recombinase 16%
• Diphtheria Toxin 16%
• Specific Genes 16%
• Venom 16%
• Mouse Strain 16%
• Allergic Reaction 16%
• Mucosal Surfaces 16%
• Contact Sites 16%
• C-kit 16%
• Inducible Expression 16%
• Fluorescent Reporter 16%
• Selective Ablation 16%
• Tamoxifen Inducible 16%
• Efficient Ablation 16%
• Mast Cell-specific Conditional Gene Targeting 16%
• High Efficiency 16%
• Genetic Toolbox 16%

Immunology and Microbiology

• Mast Cell 100%
• Gene Locus 100%
• Gene Targeting 100%
• Homeostasis 28%
• Innate Immune System 14%
• Adaptive Immune System 14%
• Hypersensitive Response 14%
• Immune Response 14%
• Cell Function 14%
• Cell Maturation 14%
• Gene Expression 14%
• Mouse Strain 14%
• Hematopoietic Cell 14%