Concept for a gas-cell-driven drug delivery system for therapeutic applications

S. Becker; T. Xu; F. Ilchmann; J. Eisler; B. Wolf

doi:10.1177/0954411911423348

Concept for a gas-cell-driven drug delivery system for therapeutic applications

S. Becker, T. Xu, F. Ilchmann, J. Eisler, B. Wolf

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Technische Universität München

Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

5 Zitate (Scopus)

Abstract

This paper presents a concept for an implantable micro-pump based on hydrogen- generating gas cells. The gas-generating cell is separated from the drug reservoir by an expandable latex membrane. The system offers linear drug delivery with flowrates ranging from 8-nl/s to 2-μl/s and a total delivery volume of up to 160-ml. Drugs can be dispensed over a wide backpressure range. The device is scalable based on the size of the gas-producing cell and requires no external energy source. Possible fields of application include in vivo local drug delivery for chemotherapy, diabetes, and pain management.

Originalsprache	Englisch
Seiten (von - bis)	1196-1201
Seitenumfang	6
Fachzeitschrift	Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine
Jahrgang	225
Ausgabenummer	12
DOIs	https://doi.org/10.1177/0954411911423348
Publikationsstatus	Veröffentlicht - Dez. 2011

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abstract = "This paper presents a concept for an implantable micro-pump based on hydrogen- generating gas cells. The gas-generating cell is separated from the drug reservoir by an expandable latex membrane. The system offers linear drug delivery with flowrates ranging from 8-nl/s to 2-μl/s and a total delivery volume of up to 160-ml. Drugs can be dispensed over a wide backpressure range. The device is scalable based on the size of the gas-producing cell and requires no external energy source. Possible fields of application include in vivo local drug delivery for chemotherapy, diabetes, and pain management.",

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AU - Wolf, B.

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Concept for a gas-cell-driven drug delivery system for therapeutic applications

Abstract

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