Comparative functional analysis reveals differential nucleotide sensitivity between human and mouse UCP1

Keyphrases

• Acid Activation 22%
• Activity Feature 11%
• Activity Regulation 11%
• Brown Adipose Tissue 11%
• Doxycycline 11%
• Fatty Acids 22%
• Free Fatty Acids 11%
• Functional Analysis 100%
• Functional Studies 11%
• Helix 22%
• Induced Activity 22%
• Inhibitory Potential 11%
• Metabolic Disease 11%
• Mitochondrial Carrier 11%
• Mitochondrial Inner Membrane 11%
• Mitochondrial Uncoupling Protein 11%
• Mutagenesis 11%
• Mutant Variants 11%
• Net-proton 11%
• Nonconserved Residues 11%
• Orthologs 11%
• Pharmacological Targets 11%
• Proton Flux 11%
• Purine nucleotides 22%
• Respirometry 11%
• Rodent Models 11%
• Structural Features 11%
• Structure-function Relationship 11%
• Thermogenic 11%
• Uncoupling Protein 1 (UCP1) 100%
• Unique Proteins 11%

Biochemistry, Genetics and Molecular Biology

• Free Fatty Acids 10%
• Inner Mitochondrial Membrane 10%
• Metabolic Disorder 10%
• Mitochondrial Carrier 10%
• Mutagenesis 10%
• Orthology 10%
• Synapsin I 100%
• Uncoupling Protein 100%
• Wild Type 10%