Cognate interaction between endothelial cells and T cells

Publikation: Beitrag in Buch/Bericht/KonferenzbandKapitelBegutachtung

11 Zitate (Scopus)

Abstract

Endothelial cells lining the blood vessels form a barrier between circulating immune cells and parenchymal tissue. While the molecular mechanisms involved in antigen-independent recruitment of leukocytes into infected tissue have been extensively studied, the mechanisms involving antigen-specific recruitment of T cells into tissue have remained largely elusive. Here I shall review the experimental evidence that endothelial cells function as antigen-presenting cells and in this function contribute first to regulation of immune responses and second, to antigen-specific recruitment of T cells.

OriginalspracheEnglisch
TitelCell Communication in Nervous and Immune System
Redakteure/-innenEckhart Gundelfinger, Constanze Seidenbecher, Bukhart Schraven
Seiten151-173
Seitenumfang23
DOIs
PublikationsstatusVeröffentlicht - 2006
Extern publiziertJa

Publikationsreihe

NameResults and Problems in Cell Differentiation
Band43
ISSN (Print)0080-1844
ISSN (elektronisch)1861-0412

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