Clinical impact of the plasminogen activation system in tumor invasion and metastasis: Prognostic relevance and target for therapy

Keyphrases

• Clinical Impact 100%
• Prognostic Relevance 100%
• Tumor Metastasis 100%
• Targets for Therapy 100%
• Urokinase-type Plasminogen Activator 100%
• Tumor Invasion 100%
• Plasminogen Activation System 100%
• Plasminogen Activator inhibitor-1 (PAI-1) 40%
• Overall Survival 20%
• Malignant Solid Tumors 20%
• CD87 20%
• Kidney Tissue 10%
• Protein Level 10%
• Metastasis 10%
• Basement Membrane 10%
• Soft Tissue 10%
• Breast Cancer 10%
• Brain Tissue 10%
• In Cancer 10%
• Lung Tissue 10%
• Cancer Cells 10%
• Strong Correlation 10%
• Tumor Cells 10%
• Breast Tissue 10%
• Bladder 10%
• Recurrent Disease 10%
• Prognostic Value 10%
• Tumor Progression 10%
• Recombinant 10%
• Proteolysis 10%
• Cancer Tissue 10%
• Patients with Cancer 10%
• Plasmin 10%
• Prognostic Marker 10%
• Extracellular Matrix 10%
• Antisense Oligonucleotides 10%
• Endometrial Tissue 10%
• Disease-free 10%
• Tumor Cell Migration 10%
• Ovarian Tissue 10%
• Serine Protease 10%
• Cancer Metastasis 10%
• Cancer Invasion 10%
• Enzyme Inhibitors 10%
• Primary Cancer 10%
• Activator Type 10%
• Cervical Tissue 10%
• Intravasation 10%
• PAI-2 10%
• Tumor-associated 10%
• Gene Level 10%
• Colon Tissue 10%
• Stomach Tissue 10%

Medicine and Dentistry

• Metastatic Carcinoma 100%
• Urokinase 100%
• Tumor Invasion 100%
• Plasminogen Activation 100%
• Plasminogen Activator Inhibitor-1 50%
• Tumor Cell 25%
• Overall Survival 25%
• Solid Malignant Neoplasm 25%
• Neoplasm 12%
• Disease 12%
• Colon 12%
• Protein Degradation 12%
• Malignant Neoplasm 12%
• Recurrent Disease 12%
• Bladder 12%
• Cancer Cell 12%
• Tumor Progression 12%
• Cervix 12%
• Extracellular Matrix 12%
• Primary Tumor 12%
• Fibrinolysin 12%
• Cancer Tissue 12%
• Endometrium 12%
• Serine Proteinase 12%
• Extravasation 12%
• Antisense Oligonucleotide 12%
• Basement Membrane 12%
• Plasminogen Activator Inhibitor-2 12%
• Enzyme Inhibitor 12%
• Intravasation 12%
• Cell Migration 12%
• Urokinase Receptor 12%

Pharmacology, Toxicology and Pharmaceutical Science

• Plasminogen 100%
• Metastasis 100%
• Tumor Invasion 100%
• Urokinase 100%
• Malignant Neoplasm 37%
• Neoplasm 37%
• Solid Malignant Neoplasm 25%
• Overall Survival 25%
• Tumor Growth 12%
• Recurrent Disease 12%
• Serine Proteinase 12%
• Antisense Oligonucleotide 12%
• Plasmin 12%
• Disease 12%
• Primary Tumor 12%
• Enzyme Inhibitor 12%
• Extravasation 12%
• Urokinase Receptor 12%