Chemokine Receptor 4 Expression in Primary Sjögren's Syndrome

Wojciech Cytawa; Stefan Kircher; Andreas Schirbel; Takahiro Shirai; Kazuhito Fukushima; Andreas K. Buck; Hans Jürgen Wester; Constantin Lapa

doi:10.1097/RLU.0000000000002258

Chemokine Receptor 4 Expression in Primary Sjögren's Syndrome

Wojciech Cytawa, Stefan Kircher, Andreas Schirbel, Takahiro Shirai, Kazuhito Fukushima, Andreas K. Buck, Hans Jürgen Wester, Constantin Lapa

Lehrstuhl für Pharmazeutische Radiochemie

Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

18 Zitate (Scopus)

Abstract

⁶⁸Ga-pentixafor is a novel radioligand of C-X-C motif chemokine receptor 4. A 55-year-old woman with a history of primary Sjögren's syndrome underwent ⁶⁸Ga-pentixafor PET/CT for staging of lymphoma originating from mucosa-associated lymphoid tissue. Whereas no lymphoma manifestation could be detected, imaging revealed bilateral intense radiotracer uptake in both parotid and submandibular salivary glands, consistent with inflammatory cell infiltration.

Originalsprache	Englisch
Seiten (von - bis)	835-836
Seitenumfang	2
Fachzeitschrift	Clinical nuclear medicine
Jahrgang	43
Ausgabenummer	11
DOIs	https://doi.org/10.1097/RLU.0000000000002258
Publikationsstatus	Veröffentlicht - 1 Nov. 2018

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10.1097/RLU.0000000000002258

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title = "Chemokine Receptor 4 Expression in Primary Sj{\"o}gren's Syndrome",

abstract = "68Ga-pentixafor is a novel radioligand of C-X-C motif chemokine receptor 4. A 55-year-old woman with a history of primary Sj{\"o}gren's syndrome underwent 68Ga-pentixafor PET/CT for staging of lymphoma originating from mucosa-associated lymphoid tissue. Whereas no lymphoma manifestation could be detected, imaging revealed bilateral intense radiotracer uptake in both parotid and submandibular salivary glands, consistent with inflammatory cell infiltration.",

keywords = "CXCR4, PET, Sj{\"o}gren's syndrome, lymphoma",

author = "Wojciech Cytawa and Stefan Kircher and Andreas Schirbel and Takahiro Shirai and Kazuhito Fukushima and Buck, \{Andreas K.\} and Wester, \{Hans J{\"u}rgen\} and Constantin Lapa",

year = "2018",

month = nov,

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doi = "10.1097/RLU.0000000000002258",

language = "English",

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T1 - Chemokine Receptor 4 Expression in Primary Sjögren's Syndrome

AU - Cytawa, Wojciech

AU - Kircher, Stefan

AU - Schirbel, Andreas

AU - Shirai, Takahiro

AU - Fukushima, Kazuhito

AU - Buck, Andreas K.

AU - Wester, Hans Jürgen

AU - Lapa, Constantin

PY - 2018/11/1

Y1 - 2018/11/1

N2 - 68Ga-pentixafor is a novel radioligand of C-X-C motif chemokine receptor 4. A 55-year-old woman with a history of primary Sjögren's syndrome underwent 68Ga-pentixafor PET/CT for staging of lymphoma originating from mucosa-associated lymphoid tissue. Whereas no lymphoma manifestation could be detected, imaging revealed bilateral intense radiotracer uptake in both parotid and submandibular salivary glands, consistent with inflammatory cell infiltration.

AB - 68Ga-pentixafor is a novel radioligand of C-X-C motif chemokine receptor 4. A 55-year-old woman with a history of primary Sjögren's syndrome underwent 68Ga-pentixafor PET/CT for staging of lymphoma originating from mucosa-associated lymphoid tissue. Whereas no lymphoma manifestation could be detected, imaging revealed bilateral intense radiotracer uptake in both parotid and submandibular salivary glands, consistent with inflammatory cell infiltration.

KW - CXCR4

KW - PET

KW - Sjögren's syndrome

KW - lymphoma

UR - http://www.scopus.com/inward/record.url?scp=85054452193&partnerID=8YFLogxK

U2 - 10.1097/RLU.0000000000002258

DO - 10.1097/RLU.0000000000002258

M3 - Article

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AN - SCOPUS:85054452193

SN - 0363-9762

VL - 43

SP - 835

EP - 836

JO - Clinical nuclear medicine

JF - Clinical nuclear medicine

IS - 11

ER -

Chemokine Receptor 4 Expression in Primary Sjögren's Syndrome

Abstract

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