Charting the Roadmap of T Cell Exhaustion

Talyn Chu; Dietmar Zehn

doi:10.1016/j.immuni.2020.04.019

Charting the Roadmap of T Cell Exhaustion

Talyn Chu
, Dietmar Zehn

Lehrstuhl für Tierphysiologie und Immunologie

Technische Universität München

Publikation: Beitrag in Fachzeitschrift › Kommentar/Debatte

21 Zitate (Scopus)

Abstract

Exposure to chronic infection or malignant tumors triggers the differentiation of functionally impaired, so-called exhausted T cells. In this issue of Immunity, Beltra et al. reveal a multi-step developmental process that defines how T cells transition from proliferating progenitors into terminally differentiated exhausted T cells.

Originalsprache	Englisch
Seiten (von - bis)	724-726
Seitenumfang	3
Fachzeitschrift	Immunity
Jahrgang	52
Ausgabenummer	5
DOIs	https://doi.org/10.1016/j.immuni.2020.04.019
Publikationsstatus	Veröffentlicht - 19 Mai 2020

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10.1016/j.immuni.2020.04.019

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abstract = "Exposure to chronic infection or malignant tumors triggers the differentiation of functionally impaired, so-called exhausted T cells. In this issue of Immunity, Beltra et al. reveal a multi-step developmental process that defines how T cells transition from proliferating progenitors into terminally differentiated exhausted T cells.",

author = "Talyn Chu and Dietmar Zehn",

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DO - 10.1016/j.immuni.2020.04.019

M3 - Comment/debate

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Charting the Roadmap of T Cell Exhaustion

Abstract

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