Chapter 6: Disentangling Intercompartment Exchange from Restricted Diffusion

Mathias Schillmaier, Athanasia Kaika, Franz Schilling

Publikation: Beitrag in Buch/Bericht/KonferenzbandKapitelBegutachtung

5 Zitate (Scopus)

Abstract

Non-invasive assessment of intercompartment water exchange may be of importance to characterize pathologies which are subject to changes in membrane permeability either caused by the malignancy or as an effect of intervention. Conventional diffusion MRI is not specific to water exchange since it cannot separate the effects of exchange and restricted diffusion. For this purpose, advanced diffusion strategies based on a double-diffusion encoding have been developed to disentangle them. In this work, diffusion-based magnetic resonance methods and applications for the measurement of intercompartment exchange are reviewed.

OriginalspracheEnglisch
TitelIn-cell NMR Spectroscopy
UntertitelFrom Molecular Sciences to Cell Biology
Redakteure/-innenDaniel Topgaard
Herausgeber (Verlag)Royal Society of Chemistry
Seiten154-185
Seitenumfang32
Auflage24
DOIs
PublikationsstatusVeröffentlicht - 2020

Publikationsreihe

NameNew Developments in NMR
Nummer24
Band2020-January
ISSN (Print)2044-253X
ISSN (elektronisch)2044-2548

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