Bidirectional modulation of TCA cycle metabolites and anaplerosis by metformin and its combination with SGLT2i

Makoto Harada, Jonathan Adam, Marcela Covic, Jianhong Ge, Stefan Brandmaier, Caroline Muschet, Jialing Huang, Siyu Han, Martina Rommel, Markus Rotter, Margit Heier, Robert P. Mohney, Jan Krumsiek, Gabi Kastenmüller, Wolfgang Rathmann, Zhongmei Zou, Sven Zukunft, Markus F. Scheerer, Susanne Neschen, Jerzy AdamskiChristian Gieger, Annette Peters, Donna P. Ankerst, Thomas Meitinger, Tanya L. Alderete, Martin Hrabe de Angelis, Karsten Suhre, Rui Wang-Sattler

Helmholtz Zentrum München German Research Center for Environmental Health
German Centre for Diabetes Research (DZD)
Technische Universität München
University Hospital of Augsburg
Metabolon, Inc.
Heinrich-Heine-University
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College
National University of Singapore
University of Ljubljana
University of Munich
University of Colorado Boulder
Qatar Foundation

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Bidirectional modulation of TCA cycle metabolites and anaplerosis by metformin and its combination with SGLT2i

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Biochemistry, Genetics and Molecular Biology

Pharmacology, Toxicology and Pharmaceutical Science

Medicine and Dentistry