Back to the Future: Effector Fate during T Cell Exhaustion

Veit R. Buchholz; Dirk H. Busch

doi:10.1016/j.immuni.2019.11.007

Back to the Future: Effector Fate during T Cell Exhaustion

Veit R. Buchholz, Dirk H. Busch

Lehrstuhl für Medizinische Mikrobiologie, Immunologie und Hygiene

Publikation: Beitrag in Fachzeitschrift › Kurzer Abriss › Begutachtung

16 Zitate (Scopus)

Abstract

Exhausted CD8⁺ T cells adopt a functionally attenuated state but still confer a certain degree of pathogen control. Chen et al. (2019), Hudson et al. (2019), and Zander et al. (2019) assign the lasting maintenance of this restrained pathogen control to an equilibrium of effector-like, transitory, terminal, and memory-like exhausted T cells.

Originalsprache	Englisch
Seiten (von - bis)	970-972
Seitenumfang	3
Fachzeitschrift	Immunity
Jahrgang	51
Ausgabenummer	6
DOIs	https://doi.org/10.1016/j.immuni.2019.11.007
Publikationsstatus	Veröffentlicht - 17 Dez. 2019

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abstract = "Exhausted CD8+ T cells adopt a functionally attenuated state but still confer a certain degree of pathogen control. Chen et al. (2019), Hudson et al. (2019), and Zander et al. (2019) assign the lasting maintenance of this restrained pathogen control to an equilibrium of effector-like, transitory, terminal, and memory-like exhausted T cells.",

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Back to the Future: Effector Fate during T Cell Exhaustion

Abstract

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