Anthrazyklininduzierte kardiomyopathie im kindesalter: Pathogenese, diagnostik und therapie

Anthracycline-induced cardiomyopathy is a major problem in the long-term follow-up of patients with childhood malignancies. Several pathomechanisms have to be discussed and a multifactorial genesis is most likely. Echocardiography is an important tool in diagnosing failing myocardium, whereas stress testing has the highest sensitivity. Several therapeutic options are recommended and early treatment of subclinical forms has a positive influence on the long-term prognosis.