AMP modifications as strategies of bacterial pathogens

Aymelt Itzen

doi:10.1007/s12268-016-0697-9

AMP modifications as strategies of bacterial pathogens

Titel in Übersetzung: AMP-Modifikationen als Strategien bakterieller Krankheitserreger

Aymelt Itzen

Professur für Siliciumchemie

Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

Abstract

Bacterial pathogens have evolved with enzyme activities that may hijack intracellular signaling of mammalian cells to establish an infection. Of particular interest is a novel posttranslational modification referred to as adenylylation: An adenosine monophosphate group is covalently transferred to a mammalian target protein. Here, I discuss the consequences of adenylylation and its related modifications by Fic enzymes. Also, I comment on potential applications for protein labeling.

Titel in Übersetzung	AMP-Modifikationen als Strategien bakterieller Krankheitserreger
Originalsprache	Englisch
Seiten (von - bis)	359-361
Seitenumfang	3
Fachzeitschrift	BioSpektrum
Jahrgang	22
Ausgabenummer	4
DOIs	https://doi.org/10.1007/s12268-016-0697-9
Publikationsstatus	Veröffentlicht - Juni 2016

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10.1007/s12268-016-0697-9

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abstract = "Bacterial pathogens have evolved with enzyme activities that may hijack intracellular signaling of mammalian cells to establish an infection. Of particular interest is a novel posttranslational modification referred to as adenylylation: An adenosine monophosphate group is covalently transferred to a mammalian target protein. Here, I discuss the consequences of adenylylation and its related modifications by Fic enzymes. Also, I comment on potential applications for protein labeling.",

author = "Aymelt Itzen",

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year = "2016",

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AMP modifications as strategies of bacterial pathogens

Abstract

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