Activation of the complement system by synthetic DNA complexes: A potential barrier for intravenous gene delivery

Keyphrases

• Amine Content 28%
• Cationic Lipids 57%
• Chain Length 28%
• Charge Ratio 28%
• Complement Activation 100%
• Complement System 100%
• Complex Formulation 14%
• DC-Chol 14%
• Dendrimer 14%
• DNA Complex 100%
• DOTAP 14%
• DOTMA 14%
• Fifth Generation 14%
• Gene Delivery 100%
• Gene Delivery System 14%
• Incubation 14%
• Lipid-based Formulation 14%
• Lipid-DNA 14%
• Monovalent Cations 14%
• Oligolysine 14%
• Poly(L-lysine) Dendrimer 14%
• Poly-L-lysine 71%
• Polyamidoamine (PAMAM) 14%
• Polycation 14%
• Polyethylene Glycol 14%
• Polyethyleneimine 42%
• Positive Charge 14%
• Potential Barrier 100%
• Short Chain 14%
• Synthetic DNA 100%
• Transferrin 14%

Pharmacology, Toxicology and Pharmaceutical Science

• 1,2 Dioleoyl 3 Trimethylammoniopropane 16%
• Dendrimer 50%
• Gene Delivery 100%
• Liposome 16%
• Macrogol 16%
• Poly(amidoamine) 16%
• Polycation 16%
• Polyethyleneimine 50%
• Polylysine 100%
• Synthetic DNA 100%
• Transferrin 16%

Immunology and Microbiology

• Complement Activation 100%
• Complement System 100%
• Gene Targeting 100%
• Polylysine 85%