TY - JOUR
T1 - A Synthetic Total Impulse Response Characterization Method for Correction of Hand-Held Optoacoustic Images
AU - Chowdhury, Kaushik Basak
AU - Prakash, Jaya
AU - Karlas, Angelos
AU - Jüstel, Dominik
AU - Ntziachristos, Vasilis
N1 - Publisher Copyright:
© 2020 IEEE.
PY - 2020/10
Y1 - 2020/10
N2 - The impulse response of optoacoustic (photoacoustic) tomographic imaging system depends on several system components, the characteristics of which can influence the quality of reconstructed images. The effect of these system components on reconstruction quality have not been considered in detail so far. Here we combine sparse measurements of the total impulse response (TIR) with a geometric acoustic model to obtain a full characterization of the TIR of a handheld optoacoustic tomography system with concave limited-view acquisition geometry. We then use this synthetic TIR to reconstruct data from phantoms and healthy human volunteers, demonstrating improvements in image resolution and fidelity. The higher accuracy of optoacoustic tomographic reconstruction with TIR correction further improves the diagnostic capability of handheld optoacoustic tomographic systems.
AB - The impulse response of optoacoustic (photoacoustic) tomographic imaging system depends on several system components, the characteristics of which can influence the quality of reconstructed images. The effect of these system components on reconstruction quality have not been considered in detail so far. Here we combine sparse measurements of the total impulse response (TIR) with a geometric acoustic model to obtain a full characterization of the TIR of a handheld optoacoustic tomography system with concave limited-view acquisition geometry. We then use this synthetic TIR to reconstruct data from phantoms and healthy human volunteers, demonstrating improvements in image resolution and fidelity. The higher accuracy of optoacoustic tomographic reconstruction with TIR correction further improves the diagnostic capability of handheld optoacoustic tomographic systems.
KW - Handheld transducer probe
KW - Image reconstruction
KW - Photoacoustic tomography
KW - Total impulse response
KW - Transducer modeling
UR - http://www.scopus.com/inward/record.url?scp=85092680595&partnerID=8YFLogxK
U2 - 10.1109/TMI.2020.2989236
DO - 10.1109/TMI.2020.2989236
M3 - Article
C2 - 32324545
AN - SCOPUS:85092680595
SN - 0278-0062
VL - 39
SP - 3218
EP - 3230
JO - IEEE Transactions on Medical Imaging
JF - IEEE Transactions on Medical Imaging
IS - 10
M1 - 9075254
ER -