A patient-enriched MEIS1 coding variant causes a restless legs syndrome-like phenotype in mice

Keyphrases

• MEIS1 100%
• Restless Legs Syndrome 100%
• Coding Variants 100%
• Aged Mice 27%
• Age-dependent 18%
• Rest Period 18%
• Neurological Disorders 9%
• Tactile Feedback 9%
• Point mutation 9%
• Missense Variants 9%
• Hyperactivity 9%
• Genetic Association 9%
• Non-carriers 9%
• Wheel Running 9%
• Littermate 9%
• During Pregnancy 9%
• Female Mice 9%
• Hot Plate 9%
• Sensorimotor Function 9%
• Syndrome Model 9%
• Clinically Relevant Variants 9%
• Sleep Disruption 9%
• Rotarod 9%
• Aged Female 9%
• Sensory Experiments 9%

Biochemistry, Genetics and Molecular Biology

• Mouse 100%
• MEIS1 100%
• Missense 12%
• Unpleasant Sensation 12%
• Point Mutation 12%
• Genetic Association 12%
• Tactile Feedback 12%
• Sensation 12%

Neuroscience

• MEIS1 100%
• Restless Legs Syndrome 100%
• Behavior (Neuroscience) 9%
• Neurological Disorder 9%
• Point Mutation 9%
• Hyperactivity 9%