A general and practical oxidation of alcohols to primary amides under metal-free conditions

Xiao Feng Wu, Muhammad Sharif, Jian Bo Feng, Helfried Neumann, Anahit Pews-Davtyan, Peter Langer, Matthias Beller

Publikation: Beitrag in FachzeitschriftArtikelBegutachtung

39 Zitate (Scopus)

Abstract

A general procedure for oxidation of both benzyl alcohols and alkyl alcohols to primary amides under catalyst free conditions has been developed. 34 examples of primary amides were produced from their corresponding alcohols in moderate to excellent yields. This is a practical procedure for primary amides synthesis; water and tert-butanol are the only by-products. A commercial drug, Piracetam, was prepared in one step with 73% yield as well.

OriginalspracheEnglisch
Seiten (von - bis)1956-1961
Seitenumfang6
FachzeitschriftGreen Chemistry
Jahrgang15
Ausgabenummer7
DOIs
PublikationsstatusVeröffentlicht - Juli 2013
Extern publiziertJa

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