Abstract
In the course of studies directed toward the discovery of novel scaffolds for medicinal application, we synthesized a series of 3-substituted indolizine-1-carbonitrile derivatives. Some of them displayed activity against MPtpA/MPtpB phosphatases which are involved in infectious diseases. We report here the solid-phase synthesis and antiphosphatase activity of a series of indolizines.
Originalsprache | Englisch |
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Seiten (von - bis) | 59-63 |
Seitenumfang | 5 |
Fachzeitschrift | Bioorganic and Medicinal Chemistry Letters |
Jahrgang | 16 |
Ausgabenummer | 1 |
DOIs | |
Publikationsstatus | Veröffentlicht - 1 Jan. 2006 |