2.26 MicroRNA as biomaterial

E. R. Balmayor; S. Font Tellado; M. Van Griensven

doi:10.1016/B978-0-12-803581-8.09320-6

2.26 MicroRNA as biomaterial

E. R. Balmayor, S. Font Tellado, M. Van Griensven

TUM - Lehrstuhl für Architekturinformatik, Prof. Dr.-Ing. Frank Petzold

Publikation: Beitrag in Buch/Bericht/Konferenzband › Kapitel › Begutachtung

1 Zitat (Scopus)

Abstract

MicroRNA (miRNA) are master regulators of gene expression and impact cell proliferation, differentiation and apoptosis among others. They interact with their target messenger RNA to exert their function. Lately, miRNAs have been associated to many human diseases and their potential as biomarkers and therapeutic has been highlighted. The process of miRNA biogenesis and function is shown. Moreover, miRNA applications in medicine are presented in disease diagnosis or therapeutic use. The latter is presented in detail and illustrated with examples. Special attention is dedicated to the use of biomaterials loaded with miRNAs and their use in tissue engineering and regenerative medicine.

Originalsprache	Englisch
Titel	Comprehensive Biomaterials II
Herausgeber (Verlag)	Elsevier
Seiten	558-570
Seitenumfang	13
ISBN (elektronisch)	9780081006924
ISBN (Print)	9780081006917
DOIs	https://doi.org/10.1016/B978-0-12-803581-8.09320-6
Publikationsstatus	Veröffentlicht - 1 Jan. 2017
Extern publiziert	Ja

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abstract = "MicroRNA (miRNA) are master regulators of gene expression and impact cell proliferation, differentiation and apoptosis among others. They interact with their target messenger RNA to exert their function. Lately, miRNAs have been associated to many human diseases and their potential as biomarkers and therapeutic has been highlighted. The process of miRNA biogenesis and function is shown. Moreover, miRNA applications in medicine are presented in disease diagnosis or therapeutic use. The latter is presented in detail and illustrated with examples. Special attention is dedicated to the use of biomaterials loaded with miRNAs and their use in tissue engineering and regenerative medicine.",

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AU - Balmayor, E. R.

AU - Tellado, S. Font

AU - Van Griensven, M.

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AB - MicroRNA (miRNA) are master regulators of gene expression and impact cell proliferation, differentiation and apoptosis among others. They interact with their target messenger RNA to exert their function. Lately, miRNAs have been associated to many human diseases and their potential as biomarkers and therapeutic has been highlighted. The process of miRNA biogenesis and function is shown. Moreover, miRNA applications in medicine are presented in disease diagnosis or therapeutic use. The latter is presented in detail and illustrated with examples. Special attention is dedicated to the use of biomaterials loaded with miRNAs and their use in tissue engineering and regenerative medicine.

KW - Antagomir

KW - Antisense oligonucleotides

KW - Biomaterials

KW - Mimics

KW - Regenerative medicine

KW - Small molecules inhibitors of miRNA

KW - miRNA biogenesis

KW - miRNA cellular function

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SN - 9780081006917

SP - 558

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BT - Comprehensive Biomaterials II

PB - Elsevier

ER -

2.26 MicroRNA as biomaterial

Abstract

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