Keyphrases
Amyloid Precursor Protein
100%
Secretase
86%
Alzheimer's Disease
82%
β-site APP-cleaving Enzyme 1 (BACE1)
67%
Protease
65%
Metalloprotease
46%
Disintegrin
38%
ADAM10
36%
Ectodomain Shedding
28%
Alzheimer's Disease Model
24%
Membrane Protein
23%
Ectodomain
21%
Seizure
20%
ADAM17
20%
Transmembrane Domain
20%
Signal Peptidase
19%
Cleavage Site
18%
Amyloid-β Peptide
18%
Microglia
18%
Mouse Brain
17%
Metalloproteinases
16%
Alzheimer
15%
BACE1 Inhibitor
14%
Secretome
13%
Cell Surface
13%
Drug Target
12%
Cerebrospinal Fluid
12%
Triggering Receptor Expressed on Myeloid Cells 2 (TREM2)
12%
Plaque
12%
Proteomics
12%
Regulated Intramembrane Proteolysis
11%
Neurodegenerative Diseases
11%
Amyloid beta
10%
Aspartic Protease
10%
Hippocampal Neurons
10%
Nervous System
10%
Central Nervous System
9%
BACE1 Inhibition
9%
Protein Enrichment
9%
Presenilin
9%
Transmembrane Protein
9%
Primary Neurons
9%
Protein Trafficking
9%
Rhomboid
9%
Human Amyloid Precursor Protein
9%
BACE2
8%
Amyloid Plaques
8%
Surface Expression
8%
Physiological Function
8%
Proteolytic Processing
8%
Biochemistry, Genetics and Molecular Biology
Amyloid Precursor Protein
99%
Protease
91%
Secretase
80%
Amyloid Protein
57%
Proteomics
47%
Metalloproteinase
47%
Metalloendopeptidase
47%
Ectodomain
46%
ADAM10
34%
Disintegrin
30%
Proteolysis
23%
Enzyme
23%
Mouse Model
22%
ADAM17
21%
Secretome
21%
Transmembrane Domain
20%
Liquid
18%
Proteome
18%
Signal Peptide Peptidase
16%
C-Terminus
15%
Secretion (Process)
15%
Mass Spectrometry
13%
Quantitative Proteomics
13%
Membrane Protein
13%
Aspartic Acid
12%
Microglia
12%
Transmembrane Protein
12%
Precursor
12%
Prion Protein
11%
NPC1
11%
Synapsin I
10%
Beta-Secretase 1
10%
Click
10%
Sorting Nexin
10%
Glycosylation
10%
Protein Targeting
9%
Posttranslational Modification
9%
Synapse
9%
Transgenic Mouse
9%
N-Terminus
9%
Tumor Necrosis Factor
8%
Cell Membrane
8%
Dendritic Spine
8%
Tau
8%
Endocytosis
8%
Alpha Secretase
7%
Proteolytic Processing
7%
Autosomal Dominant Inheritance
7%
Mitochondrion
7%
A Disintegrin and Metalloproteinase
7%
