Kathrin Lang

Publikationen

Publikationen pro Jahr 2005 2007 2008 2012 2014 2015 2017 2018 2019 2020 2021 2022 2024 2025

• 50 Artikel
• 7 Kommentar/Debatte
• 5 Übersichtsartikel
• 1 Kapitel

Publikationen pro Jahr

Publikationen pro Jahr

Suchergebnisse

• 2025

  One-pot dual protein labeling for simultaneous mechanical and fluorescent readouts in optical tweezers

  Silbermann, L. M., Fottner, M., van der Meulen, R., Migdad, N., Lang, K. & Tych, K., Apr. 2025, in: Protein Science. 34, 4, e70098.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Optical Tweezers 100%
  • Protein Labeling 100%
  • Dual Protein 100%
  • Fluorescence Resonance Energy Transfer 100%
  • Maleimide 100%

• Thoughts for the future

  Alkhalaf, L. M., Arrowsmith, C., Balskus, E. P., Bergamini, G., Bhandari, R., Chang, C. J., Chen, P., Chen, X., Ciulli, A., Cricco, J. A., Davis, B. G., Delbianco, M., Dudareva, N., Dueber, E., Ferguson, F., de Giuseppe, P. O., Hamachi, I., Hammond, M. C., Hatzios, S. K. & Do Heo, W. &29 mehr, Janet, J. P., Kamat, S. S., Knapp, S., Krishnan, Y., Lang, K., Laraia, L., Leveson-Gower, R. B., Li, X. D., Liu, D. R., Liu, M. F., London, N., Mahanta, N., Mayor-Ruiz, C., Muir, T., Murakami, M. T., Rhee, H. W., Robers, M., Satz, A., Schulman, B. A., Shen, B., Shoichet, B., Strauss, E., Suzuki, T., Tiwary, P., Waldmann, H., Ward, T. R., Weeks, A., Weerapana, E. & Winter, G., Jan. 2025, in: Nature Chemical Biology. 21, 1, S. 6-15 10 S.

  Publikation: Beitrag in Fachzeitschrift › Kommentar/Debatte

  • Biologists 100%
  • Main Field 100%
  • Chemical Biology 100%
  • Biological Sciences 100%
• 2024

  Deciphering functional roles of protein succinylation and glutarylation using genetic code expansion

  Weyh, M., Jokisch, M. L., Nguyen, T. A., Fottner, M. & Lang, K., Juni 2024, in: Nature Chemistry. 16, 6, S. 913-921 9 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Post-translational Modification 100%
  • Functional Role 100%
  • Genetic Code Expansion 100%
  • Glutarylation 100%
  • Protein Succinylation 100%
  11 Zitate (Scopus)

• DMCCB Basel Symposium 2024: Therapeutics by Computational Design: Innovations in Drug Discovery and AI

  Williams, S. R. & Lang, K., 2024, in: Chimia. 78, 7-8, S. 559-560 2 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

• Genetic Code Expansion Approaches to Decipher the Ubiquitin Code

  Wanka, V., Fottner, M., Cigler, M. & Lang, K., 2024, (Angenommen/Im Druck) in: Chemical Reviews.

  Publikation: Beitrag in Fachzeitschrift › Übersichtsartikel › Begutachtung

  Open Access

  • Genetic Code Expansion 100%
  • Ubiquitin Code 100%
  • Genetic Code 100%
  • Ubiquitin 100%
  • Post-translational Modification 40%
  1 Zitat (Scopus)

• How cycloalkane fusion enhances the cycloaddition reactivity of dibenzocyclooctynes

  Svatunek, D., Murnauer, A., Tan, Z., Houk, K. N. & Lang, K., 8 Jan. 2024, in: Chemical Science. 15, 6, S. 2229-2235 7 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Cycloaddition 100%
  • Cyclooctatetraene 100%
  • Cycloalkanes 100%
  • Dibenzocyclooctadiene 100%
  • Cyclooctyne 100%
  4 Zitate (Scopus)
• 2023

  Introducing Azomethine Imines to Chemical Biology: Bioorthogonal Reaction with Isonitriles

  Markos, A., Biedermann, M., Heimgärtner, J., Schmitt, A., Lang, K. & Wennemers, H., 13 Sept. 2023, in: Journal of the American Chemical Society. 145, 36, S. 19513-19517 5 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Chemical Biology 100%
  • Isonitrile 100%
  • Bioorthogonal Reaction 100%
  • Azomethine Imines 100%
  • Azomethine 100%
  9 Zitate (Scopus)
• 2022

  A comprehensive set of ER protein disulfide isomerase family members supports the biogenesis of proinflammatory interleukin 12 family cytokines

  Mideksa, Y. G., Aschenbrenner, I., Fux, A., Kaylani, D., Weiß, C. A. M., Nguyen, T. A., Bach, N. C., Lang, K., Sieber, S. A. & Feige, M. J., Dez. 2022, in: Journal of Biological Chemistry. 298, 12, 102677.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Family Members 100%
  • Interleukin-12 (IL-12) 100%
  • Biogenesis 100%
  • Protein Disulfide Isomerase 100%
  • Interleukin-12 Family 100%
  5 Zitate (Scopus)

• Site-Specific Protein Labeling and Generation of Defined Ubiquitin-Protein Conjugates Using an Asparaginyl Endopeptidase

  Fottner, M., Heimgärtner, J., Gantz, M., Mühlhofer, R., Nast-Kolb, T. & Lang, K., 27 Juli 2022, in: Journal of the American Chemical Society. 144, 29, S. 13118-13126 9 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Ubiquitin 100%
  • Site-directed Spin Labeling 100%
  • Protein Conjugates 100%
  • Asparaginyl Endopeptidase 100%
  • Conjugate 100%
  33 Zitate (Scopus)

• Substrate Profiling of Mitochondrial Caseinolytic Protease P via a Site-Specific Photocrosslinking Approach

  Nguyen, T. A., Gronauer, T. F., Nast-Kolb, T., Sieber, S. A. & Lang, K., 1 März 2022, in: Angewandte Chemie International Edition in English. 61, 10, e202111085.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Photocrosslinking 100%
  • Substrate Profiling 100%
  • Caseinolytic Protease P 100%
  • Protease 100%
  • Substrate Proteins 25%
  20 Zitate (Scopus)
• 2021

  A modular toolbox to generate complex polymeric ubiquitin architectures using orthogonal sortase enzymes

  Fottner, M., Weyh, M., Gaussmann, S., Schwarz, D., Sattler, M. & Lang, K., Dez. 2021, in: Nature Communications. 12, 1, 6515.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Ubiquitin 100%
  • Sortase A 100%
  • Enzyme 100%
  • Sortase 100%
  • Action Localization 16%
  44 Zitate (Scopus)

• Bioorthogonal chemistry

  Scinto, S. L., Bilodeau, D. A., Hincapie, R., Lee, W., Nguyen, S. S., Xu, M., am Ende, C. W., Finn, M. G., Lang, K., Lin, Q., Pezacki, J. P., Prescher, J. A., Robillard, M. S. & Fox, J. M., Dez. 2021, in: Nature Reviews Methods Primers. 1, 1, 30.

  Publikation: Beitrag in Fachzeitschrift › Übersichtsartikel › Begutachtung

  Open Access

  • Bioorthogonal Chemistry 100%
  • Chemistry 100%
  • High Yielding 33%
  • Bioorthogonal Reaction 33%
  • Cycloaddition 16%
  292 Zitate (Scopus)

• Identification of permissive amber suppression sites for efficient non-canonical amino acid incorporation in mammalian cells

  Bartoschek, M. D., Ugur, E., Nguyen, T. A., Rodschinka, G., Wierer, M., Lang, K. & Bultmann, S., 21 Juni 2021, in: Nucleic Acids Research. 49, 11, S. E62

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Mammalian Cells 100%
  • Amber Suppression 100%
  • Unnatural Amino Acid Incorporation 100%
  • Ncaa 100%
  • Stop Codon 100%
  38 Zitate (Scopus)

• Rab1-AMPylation by Legionella DrrA is allosterically activated by Rab1

  Du, J., Wrisberg, M. K. V., Gulen, B., Stahl, M., Pett, C., Hedberg, C., Lang, K., Schneider, S. & Itzen, A., 1 Dez. 2021, in: Nature Communications. 12, 1, 460.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Legionella 100%
  • Rab1 100%
  • AMPylation 100%
  • Binding Site 66%
  • Crystal Structure 33%
  17 Zitate (Scopus)

• Structural basis for VPS34 kinase activation by Rab1 and Rab5 on membranes

  Tremel, S., Ohashi, Y., Morado, D. R., Bertram, J., Perisic, O., Brandt, L. T. L., von Wrisberg, M. K., Chen, Z. A., Maslen, S. L., Kovtun, O., Skehel, M., Rappsilber, J., Lang, K., Munro, S., Briggs, J. A. G. & Williams, R. L., 1 Dez. 2021, in: Nature Communications. 12, 1, 1564.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Kinase Activation 100%
  • Rab1 100%
  • Rab5 100%
  • Vps34 100%
  • GTPase 100%
  60 Zitate (Scopus)
• 2020

  A methylated lysine is a switch point for conformational communication in the chaperone Hsp90

  Rehn, A., Lawatscheck, J., Jokisch, M. L., Mader, S. L., Luo, Q., Tippel, F., Blank, B., Richter, K., Lang, K., Kaila, V. R. I. & Buchner, J., 1 Dez. 2020, in: Nature Communications. 11, 1, 1219.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Heat Shock Protein 90 (Hsp90) 100%
  • Switching Point 100%
  • Methylated Lysine 100%
  • Chaperone Hsp90 100%
  • Hsp90 100%
  30 Zitate (Scopus)

• Author Correction: A methylated lysine is a switch point for conformational communication in the chaperone Hsp90 (Nature Communications, (2020), 11, 1, (1219), 10.1038/s41467-020-15048-8)

  Rehn, A., Lawatscheck, J., Jokisch, M. L., Mader, S. L., Luo, Q., Tippel, F., Blank, B., Richter, K., Lang, K., Kaila, V. R. I. & Buchner, J., 1 Dez. 2020, in: Nature Communications. 11, 1, 3727.

  Publikation: Beitrag in Fachzeitschrift › Kommentar/Debatte

  Open Access

  • Switching Point 100%
  • Methylated Lysine 100%
  • Chaperone Hsp90 100%
  • Hsp90 100%
  • Lysine 100%
  1 Zitat (Scopus)

• Decorating proteins with LACE

  Fottner, M. & Lang, K., 1 Nov. 2020, in: Nature Chemistry. 12, 11, S. 980-982 3 S.

  Publikation: Beitrag in Fachzeitschrift › Kommentar/Debatte
  4 Zitate (Scopus)

• Increasing the chemical space of proteins in living cells via genetic code expansion

  Krauskopf, K. & Lang, K., Okt. 2020, in: Current Opinion in Chemical Biology. 58, S. 112-120 9 S.

  Publikation: Beitrag in Fachzeitschrift › Übersichtsartikel › Begutachtung

  • Living Cells 100%
  • Chemical Space 100%
  • Genetic Code Expansion 100%
  • Unnatural Amino Acids 100%
  • Amino Acids 100%
  22 Zitate (Scopus)

• Site-Specific Protein Labeling with Fluorophores as a Tool To Monitor Protein Turnover

  Mideksa, Y. G., Fottner, M., Braus, S., Weiß, C. A. M., Nguyen, T. A., Meier, S., Lang, K. & Feige, M. J., 1 Juli 2020, in: ChemBioChem. 21, 13, S. 1861-1867 7 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Fluorophore 100%
  • Protein Turnover 100%
  • Site-directed Spin Labeling 100%
  • Quality Control 100%
  • Protein Degradation 100%
  11 Zitate (Scopus)
• 2019

  Expanding the genetic code with a lysine derivative bearing an enzymatically removable phenylacetyl group

  Reille-Seroussi, M., Mayer, S. V., Dörner, W., Lang, K. & Mootz, H. D., 2019, in: Chemical Communications. 55, 33, S. 4793-4796 4 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  • Escherichia Coli 100%
  • Protein Structure 100%
  • Protein Function 100%
  • Lysine 100%
  • Side-chain Modification 100%
  7 Zitate (Scopus)

• Genetically Encoded Biotin Analogues: Incorporation and Application in Bacterial and Mammalian Cells

  Hohl, A., Mideksa, Y. G., Karan, R., Akal, A., Vogler, M., Groll, M., Rueping, M., Lang, K., Feige, M. J. & Eppinger, J., 15 Juli 2019, in: ChemBioChem. 20, 14, S. 1795-1798 4 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Biotin 100%
  • Mammalian Cells 100%
  • Bacterial Cells 100%
  • Genetically Encoded 100%
  • Lysine 50%
  3 Zitate (Scopus)

• Installing Terminal-Alkyne Reactivity into Proteins in Engineered Bacteria

  Lang, K., 18 Juni 2019, in: Biochemistry. 58, 24, S. 2703-2705 3 S.

  Publikation: Beitrag in Fachzeitschrift › Kommentar/Debatte
  2 Zitate (Scopus)

• Photo-induced and Rapid Labeling of Tetrazine-Bearing Proteins via Cyclopropenone-Caged Bicyclononynes

  Mayer, S. V., Murnauer, A., von Wrisberg, M. K., Jokisch, M. L. & Lang, K., 28 Okt. 2019, in: Angewandte Chemie International Edition in English. 58, 44, S. 15876-15882 7 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Photoinduced 100%
  • Tetrazine 100%
  • Rapid Labeling 100%
  • Cyclopropenone 100%
  • Cycloaddition 100%
  67 Zitate (Scopus)

• Site-specific ubiquitylation and SUMOylation using genetic-code expansion and sortase

  Fottner, M., Brunner, A. D., Bittl, V., Horn-Ghetko, D., Jussupow, A., Kaila, V. R. I., Bremm, A. & Lang, K., 1 März 2019, in: Nature Chemical Biology. 15, 3, S. 276-284 9 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  • SUMOylation 100%
  • Ubiquitylation 100%
  • Genetic Code Expansion 100%
  • Sortase A 100%
  • Sortase 100%
  107 Zitate (Scopus)
• 2018

  Building Peptide Bonds in Haifa: The Seventh Chemical Protein Synthesis (CPS) Meeting

  Lang, K., 18 Jan. 2018, in: ChemBioChem. 19, 2, S. 115-120 6 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung
  2 Zitate (Scopus)

• Correction to: Genetic Code Expansion Enables Live-Cell and Super-Resolution Imaging of Site-Specifically Labeled Cellular Proteins (Journal of the American Chemical Society (2015): 137: (4602-4605): DOI: 10.1021/ja512838z)

  Uttamapinant, C., Howe, J. D., Lang, K., Beránek, V., Davis, L., Mahesh, M., Barry, N. P. & Chin, J. W., 24 Okt. 2018, in: Journal of the American Chemical Society. 140, 42, S. 13986 1 S.

  Publikation: Beitrag in Fachzeitschrift › Kommentar/Debatte

  Open Access

  • Living Cells 100%
  • Histogram 100%
  • Cellular Proteins 100%
  • Genetic Code Expansion 100%
  • American Chemical Society 100%
  1 Zitat (Scopus)

• Expanding the Genetic Code to Study Protein–Protein Interactions

  Nguyen, T. A., Cigler, M. & Lang, K., 26 Okt. 2018, in: Angewandte Chemie International Edition in English. 57, 44, S. 14350-14361 12 S.

  Publikation: Beitrag in Fachzeitschrift › Übersichtsartikel › Begutachtung

  • Protein-protein Interaction 100%
  • Genetic Code 100%
  • Amino Acids 100%
  • Unnatural Amino Acids 75%
  • Protein Complex 50%
  83 Zitate (Scopus)
• 2017

  Biochemie 2016: Chemie bringt Zellen im Innern zum Leuchten

  Lang, K., 1 März 2017, in: Nachrichten aus der Chemie. 65, 3, S. 305-309 5 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

• Proximity-Triggered Covalent Stabilization of Low-Affinity Protein Complexes In Vitro and In Vivo

  Cigler, M., Müller, T. G., Horn-Ghetko, D., von Wrisberg, M. K., Fottner, M., Goody, R. S., Itzen, A., Müller, M. P. & Lang, K., 4 Dez. 2017, in: Angewandte Chemie International Edition in English. 56, 49, S. 15737-15741 5 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  • Low Affinity 100%
  • Protein Complex 100%
  • Affinity Protein 100%
  • Covalent Stabilization 100%
  • Protein Complexes 100%
  63 Zitate (Scopus)

• Tetrazines in Inverse-Electron-Demand Diels-Alder Cycloadditions and Their Use in Biology

  Mayer, S. & Lang, K., 15 Feb. 2017, in: Synthesis. 49, 4, S. 830-848 19 S., ss-2016-z0743-sr.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  • Tetrazine 100%
  • Diels-Alder Cycloaddition 100%
  • Inverse Electron Demand Diels-Alder 100%
  • Inverse Electron Demand Diels-Alder Reaction 60%
  • Diels-Alder Reaction 60%
  81 Zitate (Scopus)
• 2016

  Chemistry in living systems

  Titel in Übersetzung: Chemie in lebenden systemenLang, K. & Mayer, S., 1 März 2016, in: Nachrichten aus der Chemie. 64, 3, S. 301-305 5 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung
  1 Zitat (Scopus)

• The 6th Sino–German Frontiers of Chemistry Symposium

  Jiao, L. & Lang, K., 6 Dez. 2016, in: Chemistry - An Asian Journal. 11, 23, S. 3292-3296 5 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access
• 2015

  Erratum: Optimized orthogonal translation of unnatural amino acids enables spontaneous protein double-labelling and FRET (Nature Chemistry (2014) 6:(393-403))

  Wang, K., Sachdeva, A., Cox, D. J., Wilf, N. M., Lang, K., Wallace, S., Mehl, R. A. & Chin, J. W., Feb. 2015, in: Nature Chemistry. 7, 2, S. 178 1 S.

  Publikation: Beitrag in Fachzeitschrift › Kommentar/Debatte

  Open Access

• Genetic Code Expansion Enables Live-Cell and Super-Resolution Imaging of Site-Specifically Labeled Cellular Proteins

  Uttamapinant, C., Howe, J. D., Lang, K., Beránek, V., Davis, L., Mahesh, M., Barry, N. P. & Chin, J. W., 15 Apr. 2015, in: Journal of the American Chemical Society. 137, 14, S. 4602-4605 4 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Living Cells 100%
  • Fluorescent Labeling 100%
  • Ultrastructure 100%
  • Cellular Proteins 100%
  • Genetic Code Expansion 100%
  156 Zitate (Scopus)

• Genetic encoding of unnatural amino acids for labeling proteins

  Lang, K., Davis, L. & Chin, J. W., 2015, in: Methods in molecular biology (Clifton, N.J.). 1266, S. 217-228 12 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  • Unnatural Amino Acids 100%
  • Genetic Encoding 100%
  • Genetics 100%
  • Amino Acids 100%
  • Bioorthogonal 66%
  11 Zitate (Scopus)

• Genetic encoding of unnatural amino acids for labeling proteins

  Lang, K., Davis, L. & Chin, J. W., 5 Jan. 2015, Site-Specific Protein Labeling: Methods and Protocols. Springer Science and Business Media, LLC, S. 217-228 12 S.

  Publikation: Beitrag in Buch/Bericht/Konferenzband › Kapitel › Begutachtung

  • Unnatural Amino Acids 100%
  • Genetic Encoding 100%
  • Genetics 100%
  • Amino Acids 100%
  • Bioorthogonal 66%
  10 Zitate (Scopus)

• Selective, rapid and optically switchable regulation of protein function in live mammalian cells

  Tsai, Y. H., Essig, S., James, J. R., Lang, K. & Chin, J. W., 25 Juli 2015, in: Nature Chemistry. 7, 7, S. 554-561 8 S., 2253.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Protein Function 100%
  • Bioorthogonal 100%
  • Live Mammalian Cell 100%
  • Conjugate 100%
  • Phosphotransferase 100%
  145 Zitate (Scopus)

• Site-specific glycoconjugation of protein via bioorthogonal tetrazine cycloaddition with a genetically encoded trans -cyclooctene or bicyclononyne

  Machida, T., Lang, K., Xue, L., Chin, J. W. & Winssinger, N., 20 Mai 2015, in: Bioconjugate Chemistry. 26, 5, S. 802-806 5 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Cycloaddition 100%
  • Cyclooctatetraene 100%
  • Bioorthogonal 100%
  • Genetically Encoded 100%
  • Tetrazine 100%
  42 Zitate (Scopus)
• 2014

  4′-O-substitutions determine selectivity of aminoglycoside antibiotics

  Perez-Fernandez, D., Shcherbakov, D., Matt, T., Leong, N. C., Kudyba, I., Duscha, S., Boukari, H., Patak, R., Dubbaka, S. R., Lang, K., Meyer, M., Akbergenov, R., Freihofer, P., Vaddi, S., Thommes, P., Ramakrishnan, V., Vasella, A. & Böttger, E. C., 28 Jan. 2014, in: Nature Communications. 5, 3112.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Aminoglycosides 100%
  • Aminoglycoside Antibiotics 100%
  • Bacterial Ribosome 100%
  • Aminoglycoside 100%
  • Aminoglycoside Antibiotic Agent 100%
  66 Zitate (Scopus)

• Bioorthogonal reactions for labeling proteins

  Lang, K. & Chin, J. W., 17 Jan. 2014, in: ACS Chemical Biology. 9, 1, S. 16-20 5 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung
  473 Zitate (Scopus)

• Cellular incorporation of unnatural amino acids and bioorthogonal Labeling of Proteins

  Lang, K. & Chin, J. W., 14 Mai 2014, in: Chemical Reviews. 114, 9, S. 4764-4806 43 S.

  Publikation: Beitrag in Fachzeitschrift › Übersichtsartikel › Begutachtung

  • Biomolecules 100%
  • Unnatural Amino Acids 100%
  • Amino Acid Labeling 100%
  • Bioorthogonal Labeling 100%
  • Amino Acids 100%
  870 Zitate (Scopus)

• Optimized orthogonal translation of unnatural amino acids enables spontaneous protein double-labelling and FRET

  Wang, K., Sachdeva, A., Cox, D. J., Wilf, N. W., Lang, K., Wallace, S., Mehl, R. A. & Chin, J. W., Mai 2014, in: Nature Chemistry. 6, 5, S. 393-403 11 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Double Labeling 100%
  • Unnatural Amino Acids 100%
  • Orthogonal Translation 100%
  • Amino Acids 100%
  • Fluorescence Resonance Energy Transfer 100%
  228 Zitate (Scopus)

• Proteome labeling and protein identification in specific tissues and at specific developmental stages in an animal

  Elliott, T. S., Townsley, F. M., Bianco, A., Ernst, R. J., Sachdeva, A., Elsässer, S. J., Davis, L., Lang, K., Pisa, R., Greiss, S., Lilley, K. S. & Chin, J. W., Mai 2014, in: Nature Biotechnology. 32, 5, S. 465-472 8 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Developmental Stages 100%
  • Proteome 100%
  • Protein Identification 100%
  • Recoding 100%
  • Chemoselective Modification 100%
  157 Zitate (Scopus)
• 2013

  Fluorescent imaging: Shining a light into live cells

  Lang, K. & Chin, J. W., Feb. 2013, in: Nature Chemistry. 5, 2, S. 81-82 2 S.

  Publikation: Beitrag in Fachzeitschrift › Kommentar/Debatte
  9 Zitate (Scopus)
• 2012

  Dissociation of antibacterial activity and aminoglycoside ototoxicity in the 4-monosubstituted 2-deoxystreptamine apramycin

  Matt, T., Ng, C. L., Lang, K., Sha, S. H., Akbergenov, R., Shcherbakov, D., Meyer, M., Duscha, S., Xie, J., Dubbaka, S. R., Perez-Fernandez, D., Vasella, A., Ramakrishnan, V., Schacht, J. & Böttger, E. C., 3 Juli 2012, in: Proceedings of the National Academy of Sciences of the United States of America. 109, 27, S. 10984-10989 6 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Dissociation 100%
  • Monosubstituted 100%
  • 2-deoxystreptamine 100%
  • Aminoglycoside Ototoxicity 100%
  • Apramycin 100%
  174 Zitate (Scopus)

• Expanding the genetic code of Drosophila melanogaster

  Bianco, A., Townsley, F. M., Greiss, S., Lang, K. & Chin, J. W., Sept. 2012, in: Nature Chemical Biology. 8, 9, S. 748-750 3 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  • Genetic Code 100%
  • Drosophila Melanogaster 100%
  • Amino Acid 100%
  • Amino Acids 100%
  • Developmental Stages 50%
  168 Zitate (Scopus)

• Genetically encoded norbornene directs site-specific cellular protein labelling via a rapid bioorthogonal reaction

  Lang, K., Davis, L., Torres-Kolbus, J., Chou, C., Deiters, A. & Chin, J. W., Apr. 2012, in: Nature Chemistry. 4, 4, S. 298-304 7 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Norbornene 100%
  • Mammalian Cells 100%
  • Cellular Proteins 100%
  • Bioorthogonal 100%
  • Bioorthogonal Reaction 100%
  414 Zitate (Scopus)

• Genetic encoding of bicyclononynes and trans-cyclooctenes for site-specific protein labeling in vitro and in live mammalian cells via rapid fluorogenic diels-alder reactions

  Lang, K., Davis, L., Wallace, S., Mahesh, M., Cox, D. J., Blackman, M. L., Fox, J. M. & Chin, J. W., 27 Juni 2012, in: Journal of the American Chemical Society. 134, 25, S. 10317-10320 4 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Site-directed Spin Labeling 100%
  • Cyclooctatetraene 100%
  • Diels-Alder Reaction 100%
  • Fluorogenic 100%
  • Tetrazine 100%
  442 Zitate (Scopus)
• 2011

  Traceless and site-specific ubiquitination of recombinant proteins

  Virdee, S., Kapadnis, P. B., Elliott, T., Lang, K., Madrzak, J., Nguyen, D. P., Riechmann, L. & Chin, J. W., 20 Juli 2011, in: Journal of the American Chemical Society. 133, 28, S. 10708-10711 4 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Lysine 100%
  • Ubiquitin 100%
  • Recombinant Protein 100%
  • Ubiquitination 100%
  • Traceless 100%
  160 Zitate (Scopus)