Barbara Treutlein

Publikationen

Publikationen pro Jahr 2009 2017 2018 2025

• 26 Artikel
• 3 Übersichtsartikel
• 2 Kommentar/Debatte

Publikationen pro Jahr

Publikationen pro Jahr

Suchergebnisse

• 2025

  Publisher Correction: An integrated transcriptomic cell atlas of human neural organoids (Nature, (2024), 635, 8039, (690-698), 10.1038/s41586-024-08172-8)

  Human Cell Atlas Organoid Biological Network, 9 Jan. 2025, in: Nature. 637, 8045, S. E21

  Publikation: Beitrag in Fachzeitschrift › Kommentar/Debatte

  Open Access

  • Transcriptomics 100%
  • Cell Atlas 100%
  • Fleck 100%
  • Neural Organoids 100%
• 2024

  An integrated transcriptomic cell atlas of human neural organoids

  Human Cell Atlas Organoid Biological Network, 21 Nov. 2024, in: Nature. 635, 8039, S. 690-698 9 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Transcriptomics 100%
  • Organoids 100%
  • Cell Atlas 100%
  • Neural Organoids 100%
  • And-States 100%
  14 Zitate (Scopus)
• 2022

  High temporal resolution proteome and phosphoproteome profiling of stem cell-derived hepatocyte development

  Krumm, J., Sekine, K., Samaras, P., Brazovskaja, A., Breunig, M., Yasui, R., Kleger, A., Taniguchi, H., Wilhelm, M., Treutlein, B., Camp, J. G. & Kuster, B., 29 März 2022, in: Cell Reports. 38, 13, 110604.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • High Temporal Resolution 100%
  • Proteome 100%
  • Hepatocytes 100%
  • IPSC-derived Hepatocytes 100%
  • Phosphoproteomics 100%
  11 Zitate (Scopus)

• Spatial transcriptomic and single-nucleus analysis reveals heterogeneity in a gigantic single-celled syncytium

  Gerber, T., Loureiro, C., Schramma, N., Chen, S., Jain, A., Weber, A., Weigert, A., Santel, M., Alim, K., Treutlein, B. & Camp, J. G., Feb. 2022, in: eLife. 11, e69745.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Slime Molds 100%
  • Spatial Transcriptomics 100%
  • Single-nucleus Analysis 100%
  • Syncytium 100%
  • Transcriptomics 100%
  8 Zitate (Scopus)
• 2021

  Extracellular LGALS3BP regulates neural progenitor position and relates to human cortical complexity

  Kyrousi, C., O’Neill, A. C., Brazovskaja, A., He, Z., Kielkowski, P., Coquand, L., Di Giaimo, R., D’ Andrea, P., Belka, A., Forero Echeverry, A., Mei, D., Lenge, M., Cruceanu, C., Buchsbaum, I. Y., Khattak, S., Fabien, G., Binder, E., Elmslie, F., Guerrini, R. & Baffet, A. D. &4 mehr, Sieber, S. A., Treutlein, B., Robertson, S. P. & Cappello, S., 1 Dez. 2021, in: Nature Communications. 12, 1, 6298.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Neural Progenitors 100%
  • Cortical Complexity 100%
  • LGALS3BP 100%
  • Glia 100%
  • Gyrification 100%
  31 Zitate (Scopus)
• 2019

  High-throughput single-cell transcriptomics on organoids

  Brazovskaja, A., Treutlein, B. & Camp, J. G., Feb. 2019, in: Current Opinion in Biotechnology. 55, S. 167-171 5 S.

  Publikation: Beitrag in Fachzeitschrift › Übersichtsartikel › Begutachtung

  • High-throughput 100%
  • Single-cell Transcriptomics 100%
  • Organoids 100%
  • Transcriptomics 100%
  • Organoid 100%
  64 Zitate (Scopus)
• 2018

  A novel population of hopx-dependent basal radial glial cells in the developing mouse neocortex

  Vaid, S., Camp, J. G., Hersemann, L., Oegema, C. E., Heninger, A. K., Winkler, S., Brandl, H., Sarov, M., Treutlein, B., Huttner, W. B. & Namba, T., 2018, in: Development (Cambridge). 145, 20, dev169276.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Developing Mice 100%
  • Novel Population 100%
  • Mouse Neocortex 100%
  • Radial Glial Cells 100%
  • Hopx 100%
  75 Zitate (Scopus)

• Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis

  Churko, J. M., Garg, P., Treutlein, B., Venkatasubramanian, M., Wu, H., Lee, J., Wessells, Q. N., Chen, S. Y., Chen, W. Y., Chetal, K., Mantalas, G., Neff, N., Jabart, E., Sharma, A., Nolan, G. P., Salomonis, N. & Wu, J. C., 1 Dez. 2018, in: Nature Communications. 9, 1, 4906.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Cell Population 100%
  • Cellular Heterogeneity 100%
  • Heterogeneity Analysis 100%
  • Cardiac Transcription Factors 100%
  • RNA Sequencing 100%
  144 Zitate (Scopus)

• Direct pericyte-to-neuron reprogramming via unfolding of a neural stem cell-like program

  Karow, M., Gray Camp, J., Falk, S., Gerber, T., Pataskar, A., Gac-Santel, M., Kageyama, J., Brazovskaja, A., Garding, A., Fan, W., Riedemann, T., Casamassa, A., Smiyakin, A., Schichor, C., Götz, M., Tiwari, V. K., Treutlein, B. & Berninger, B., 18 Juni 2018, in: Nature Neuroscience. 21, 7, S. 932-940 9 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Stem Cells 100%
  • Pericytes 100%
  • Reprogramming 100%
  • Neural Stem Cell 100%
  • Ascl1 66%
  94 Zitate (Scopus)

• Optimal Hypoxia Regulates Human iPSC-Derived Liver Bud Differentiation through Intercellular TGFB Signaling

  Ayabe, H., Anada, T., Kamoya, T., Sato, T., Kimura, M., Yoshizawa, E., Kikuchi, S., Ueno, Y., Sekine, K., Camp, J. G., Treutlein, B., Ferguson, A., Suzuki, O., Takebe, T. & Taniguchi, H., 14 Aug. 2018, in: Stem Cell Reports. 11, 2, S. 306-316 11 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Hypoxia 100%
  • TGF-β Signaling 100%
  • Liver Bud 100%
  • Bud Differentiation 100%
  • Human iPSC 100%
  36 Zitate (Scopus)

• ShinyCortex: Exploring single-cell transcriptome data from the developing human cortex

  Kageyama, J., Wollny, D., Treutlein, B. & Camp, J. G., 15 Mai 2018, in: Frontiers in Neuroscience. 12, MAY, 315.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Human Cortex 100%
  • Single-cell Transcriptomics 100%
  • Single-cell mRNA Sequencing 100%
  • Transcriptomic Data 100%
  • Transcriptome 100%
  9 Zitate (Scopus)

• Single-cell analysis uncovers convergence of cell identities during axolotl limb regeneration

  Gerber, T., Murawala, P., Knapp, D., Masselink, W., Schuez, M., Hermann, S., Gac-Santel, M., Nowoshilow, S., Kageyama, J., Khattak, S., Currie, J. D., Camp, J. G., Tanaka, E. M. & Treutlein, B., 26 Okt. 2018, in: Science. 362, 6413, eaaq0681.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Single-cell Analysis 100%
  • Cell Identity 100%
  • Blastema 100%
  • Axolotl 100%
  • Limb Regeneration 100%
  266 Zitate (Scopus)

• Single-cell genomics to guide human stem cell and tissue engineering

  Camp, J. G., Wollny, D. & Treutlein, B., 1 Sept. 2018, in: Nature Methods. 15, 9, S. 661-667 7 S.

  Publikation: Beitrag in Fachzeitschrift › Übersichtsartikel › Begutachtung

  Open Access

  • Tissue Engineering 100%
  • Human Stem Cells 100%
  • Single-cell Genomics 100%
  • Stem Tissue 100%
  • Stem Cell Engineering 100%
  53 Zitate (Scopus)
• 2017

  Human development: Advances in mini-brain technology

  Camp, J. G. & Treutlein, B., 3 Mai 2017, in: Nature. 545, 7652, S. 39-40 2 S.

  Publikation: Beitrag in Fachzeitschrift › Kommentar/Debatte

  Open Access
  16 Zitate (Scopus)

• Human organomics: A fresh approach to understanding human development using single-cell transcriptomics

  Gray Camp, J. & Treutlein, B., 1 Mai 2017, in: Development (Cambridge). 144, 9, S. 1584-1587 4 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Single-cell Transcriptomics 100%
  • Human Development 100%
  • Transcriptomics 100%
  • Organoids 66%
  • Single-Cell Analysis 50%
  24 Zitate (Scopus)

• Mapping heterogeneity in patient-derived melanoma cultures by single-cell RNA-seq

  Gerber, T., Willscher, E., Loeffler-Wirth, H., Hopp, L., Schadendorf, D., Schartl, M., Anderegg, U., Camp, G., Treutlein, B., Binder, H. & Kunz, M., 2017, in: Oncotarget. 8, 1, S. 846-862 17 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Patient-derived 100%
  • Melanoma 100%
  • Single-cell RNA Sequencing (scRNA-seq) 100%
  • Tumor Heterogeneity 100%
  • RNA Sequencing 100%
  67 Zitate (Scopus)

• Multilineage communication regulates human liver bud development from pluripotency

  Camp, J. G., Sekine, K., Gerber, T., Loeffler-Wirth, H., Binder, H., Gac, M., Kanton, S., Kageyama, J., Damm, G., Seehofer, D., Belicova, L., Bickle, M., Barsacchi, R., Okuda, R., Yoshizawa, E., Kimura, M., Ayabe, H., Taniguchi, H., Takebe, T. & Treutlein, B., 22 Juni 2017, in: Nature. 546, 7659, S. 533-538 6 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  • Human Liver 100%
  • Multilineage 100%
  • Pluripotency 100%
  • Bud Development 100%
  • Liver Bud 100%
  433 Zitate (Scopus)

• Rapid Chromatin Switch in the Direct Reprogramming of Fibroblasts to Neurons

  Wapinski, O. L., Lee, Q. Y., Chen, A. C., Li, R., Corces, M. R., Ang, C. E., Treutlein, B., Xiang, C., Baubet, V., Suchy, F. P., Sankar, V., Sim, S., Quake, S. R., Dahmane, N., Wernig, M. & Chang, H. Y., 26 Sept. 2017, in: Cell Reports. 20, 13, S. 3236-3247 12 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Fibroblasts 100%
  • Induced Neuronal Cells 100%
  • Ascl1 100%
  • Chromatin 100%
  • Direct Reprogramming 100%
  100 Zitate (Scopus)

• Structural reorganization of the chromatin remodeling enzyme Chd1 upon engagement with nucleosomes

  Sundaramoorthy, R., Hughes, A. L., Singh, V., Wiechens, N., Ryan, D. P., El-Mkami, H., Petoukhov, M., Svergun, D. I., Treutlein, B., Quack, S., Fischer, M., Michaelis, J., Böttcher, B., Norman, D. G. & Owen-Hughes, T., 23 März 2017, in: eLife. 6, e22510.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Structural Reorganization 100%
  • CHD1 100%
  • Chromatin Remodeling Enzymes 100%
  • Enzyme 100%
  • Chromatin Remodeling 100%
  42 Zitate (Scopus)
• 2016

  Cellular Taxonomy of the Mouse Striatum as Revealed by Single-Cell RNA-Seq

  Gokce, O., Stanley, G. M., Treutlein, B., Neff, N. F., Camp, J. G., Malenka, R. C., Rothwell, P. E., Fuccillo, M. V., Südhof, T. C. & Quake, S. R., 26 Juli 2016, in: Cell Reports. 16, 4, S. 1126-1137 12 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Single-cell RNA Sequencing (scRNA-seq) 100%
  • Cognitive Disorders 100%
  • Cell Identity 100%
  • Mouse Striatum 100%
  • Gene Expression Profiling 100%
  303 Zitate (Scopus)

• Differences and similarities between human and chimpanzee neural progenitors during cerebral cortex development

  Mora-Bermúdez, F., Badsha, F., Kanton, S., Camp, J. G., Vernot, B., Köhler, K., Voigt, B., Okita, K., Maricic, T., He, Z., Lachmann, R., Pääbo, S., Treutlein, B., Huttner, W. B. & Musacchio, A., 26 Sept. 2016, in: eLife. 5, September2016, e18683.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Chimpanzee 100%
  • Neural Progenitors 100%
  • Cerebral Cortex Development 100%
  • Nervous System Cell 100%
  • Cerebral Cortex 100%
  195 Zitate (Scopus)

• Dissecting direct reprogramming from fibroblast to neuron using single-cell RNA-seq

  Treutlein, B., Lee, Q. Y., Camp, J. G., Mall, M., Koh, W., Shariati, S. A. M., Sim, S., Neff, N. F., Skotheim, J. M., Wernig, M. & Quake, S. R., 8 Juni 2016, in: Nature. 534, 7607, S. 391-395 5 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Fibroblasts 100%
  • Single-cell RNA Sequencing (scRNA-seq) 100%
  • Direct Reprogramming 100%
  • Transcriptome 100%
  • RNA Sequencing 100%
  342 Zitate (Scopus)
• 2015

  Human cerebral organoids recapitulate gene expression programs of fetal neocortex development

  Camp, J. G., Badsha, F., Florio, M., Kanton, S., Gerber, T., Wilsch-Bräuninger, M., Lewitus, E., Sykes, A., Hevers, W., Lancaster, M., Knoblich, J. A., Lachmann, R., Pääbo, S., Huttner, W. B. & Treutlein, B., 22 Dez. 2015, in: Proceedings of the National Academy of Sciences of the United States of America. 112, 51, S. 15672-15677 6 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Gene Expression Programming 100%
  • Neocortex 100%
  • Brain Organoids 100%
  • Neocortex Development 100%
  • In Vivo 100%
  795 Zitate (Scopus)

• Lineage-negative progenitors mobilize to regenerate lung epithelium after major injury

  Vaughan, A. E., Brumwell, A. N., Xi, Y., Gotts, J. E., Brownfield, D. G., Treutlein, B., Tan, K., Tan, V., Liu, F. C., Looney, M. R., Matthay, M. A., Rock, J. R. & Chapman, H. A., 29 Jan. 2015, in: Nature. 517, 7536, S. 621-625 5 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Lung Epithelium 100%
  • Major Trauma 100%
  • Notch Signaling 100%
  • Lineage Negative 100%
  • Notch Signaling Pathway 100%
  534 Zitate (Scopus)
• 2014

  Cartography of neurexin alternative splicing mapped by single-molecule long-read mRNA sequencing

  Treutlein, B., Gokce, O., Quake, S. R. & Südhof, T. C., 1 Apr. 2014, in: Proceedings of the National Academy of Sciences of the United States of America. 111, 13, S. E1291-E1299

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Cartography 100%
  • Single Molecule 100%
  • MRNA-seq 100%
  • Alternative Splicing 100%
  • Neurexin 100%
  243 Zitate (Scopus)

• Quantitative assessment of single-cell RNA-sequencing methods

  Wu, A. R., Neff, N. F., Kalisky, T., Dalerba, P., Treutlein, B., Rothenberg, M. E., Mburu, F. M., Mantalas, G. L., Sim, S., Clarke, M. F. & Quake, S. R., 2014, in: Nature Methods. 11, 1, S. 41-46 6 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Sequence Method 100%
  • Single-cell RNA Sequencing (scRNA-seq) 100%
  • RNA 100%
  • Quantitative Technique 100%
  • RNA Sequencing 100%
  578 Zitate (Scopus)

• Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq

  Treutlein, B., Brownfield, D. G., Wu, A. R., Neff, N. F., Mantalas, G. L., Espinoza, F. H., Desai, T. J., Krasnow, M. A. & Quake, S. R., 2014, in: Nature. 509, 7500, S. 371-375 5 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Cell Population 100%
  • Lung 100%
  • Lung Epithelium 100%
  • Single-cell RNA Sequencing (scRNA-seq) 100%
  • Lineage Hierarchy 100%
  1056 Zitate (Scopus)
• 2013

  Single-molecule studies of RNA polymerases

  Michaelis, J. & Treutlein, B., 13 Nov. 2013, in: Chemical Reviews. 113, 11, S. 8377-8399 23 S.

  Publikation: Beitrag in Fachzeitschrift › Übersichtsartikel › Begutachtung

  • Single Molecule 100%
  • RNA-dependent RNA Polymerase (RdRP) 100%
  • Single-molecule Studies 100%
  • Atomic Force Microscopy 100%
  • RNA Polymerase 100%
  18 Zitate (Scopus)
• 2012

  Dynamic Architecture of a Minimal RNA Polymerase II Open Promoter Complex

  Treutlein, B., Muschielok, A., Andrecka, J., Jawhari, A., Buchen, C., Kostrewa, D., Hög, F., Cramer, P. & Michaelis, J., 27 Apr. 2012, in: Molecular Cell. 46, 2, S. 136-146 11 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • RNA Polymerase II (RNAPII) 100%
  • Dynamic Architecture 100%
  • Open Promoter Complex 100%
  • Promoter Region 100%
  • RNA Polymerase II 100%
  50 Zitate (Scopus)
• 2011

  Direct observation of single RNA polymerase processing through a single endogenous gene in a living yeast cell

  Treutlein, B. & Michaelis, J., 10 Okt. 2011, in: Angewandte Chemie International Edition in English. 50, 42, S. 9788-9790 3 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  • RNA Polymerase II (RNAPII) 100%
  • Yeast Cells 100%
  • RNA-dependent RNA Polymerase (RdRP) 100%
  • Endogenous Genes 100%
  • RNA Polymerase 100%
  4 Zitate (Scopus)
• 2009

  Nano positioning system reveals the course of upstream and nontemplate DNA within the RNA polymerase ii elongation complex

  Andrecka, J., Treutlein, B., Arcusa, M. A. I., Muschielok, A., Lewis, R., Cheung, A. C. M., Cramer, P. & Michaelis, J., 20 Juli 2009, in: Nucleic Acids Research. 37, 17, S. 5803-5809 7 S., gkp601.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • RNA Polymerase II (RNAPII) 100%
  • Nanopositioning System 100%
  • Elongation Complex 100%
  • Polymerase 100%
  • RNA Polymerase 100%
  79 Zitate (Scopus)