Professur für Festkörper-NMR-Spektroskopie

Publikationen

Publikationen pro Jahr 2000 2011 2012 2013 2015 2017 2018 2019 2020 2024

• 83 Artikel
• 4 Kapitel
• 3 Übersichtsartikel
• 2 Brief
• 1 Mehr
  • 1 Kurzer Abriss

Publikationen pro Jahr

Publikationen pro Jahr

Suchergebnisse

• 2024

  Atomic resolution structure of full-length human insulin fibrils

  Suladze, S., Sarkar, R., Rodina, N., Bokvist, K., Krewinkel, M., Scheps, D., Nagel, N., Bardiaux, B. & Reif, B., 4 Juni 2024, in: Proceedings of the National Academy of Sciences of the United States of America. 121, 23, e2401458121.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Insulin 100%
  • Atomic Structure 100%
  • Human Insulin 100%
  • Insulin Fibrils 100%
  • Amyloid Protein 100%
  1 Zitat (Scopus)

• Manual and automatic assignment of two different Aβ40 amyloid fibril polymorphs using MAS solid-state NMR spectroscopy

  Rodina, N., Sarkar, R., Tsakalos, D., Suladze, S., Niu, Z. & Reif, B., 2024, (Angenommen/Im Druck) in: Biomolecular NMR Assignments.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • MAS Solid-state NMR 100%
  • Amyloid Fibrils 100%
  • Solid-state NMR Spectroscopy 100%
  • Amyloid-β Peptide 100%
  • Fibril Polymorphism 100%

• Was starke Magnetfelder Biopolymeren entlocken

  Hagn, F., Reif, B. & Sattler, M., Apr. 2024, in: Nachrichten aus der Chemie. 72, 4, S. 73-76 4 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung
• 2023

  Liquid–liquid phase separation of amyloid-β oligomers modulates amyloid fibrils formation

  Gui, X., Feng, S., Li, Z., Li, Y., Reif, B., Shi, B. & Niu, Z., März 2023, in: Journal of Biological Chemistry. 299, 3, 102926.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Phase Separation 100%
  • Amyloid Fibrillation 100%
  • Amyloid-β Oligomers 100%
  • Amyloid Fibril 100%
  • formation 100%
  20 Zitate (Scopus)
• 2022

  Conformational Tuning of Amylin by Charged Styrene-Maleic-Acid Copolymers

  Sahoo, B. R., Souders, C. L., Watanabe-Nakayama, T., Deng, Z., Linton, H., Suladze, S., Ivanova, M. I., Reif, B., Ando, T., Martyniuk, C. J. & Ramamoorthy, A., 30 Jan. 2022, in: Journal of Molecular Biology. 434, 2, 167385.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Amylin 100%
  • Styrene-maleic Acid Copolymer 100%
  • Styrene 100%
  • Maleic Acid 100%
  • Copolymer 100%
  5 Zitate (Scopus)

• Field and magic angle spinning frequency dependence of proton resonances in rotating solids

  Xue, K., Sarkar, R., Tošner, Z. & Reif, B., 1 Juni 2022, in: Progress in Nuclear Magnetic Resonance Spectroscopy. 130-131, S. 45-59 15 S.

  Publikation: Beitrag in Fachzeitschrift › Übersichtsartikel › Begutachtung

  • Signal-to-noise Ratio 100%
  • Proton 100%
  • Frequency Dependence 100%
  • Field Angle 100%
  • Magic Angle Spinning 100%
  5 Zitate (Scopus)

• Structural insights into the interaction of antifungal peptides and ergosterol containing fungal membrane

  Mohid, S. A., Biswas, K., Won, T. J., Mallela, L. S., Gucchait, A., Butzke, L., Sarkar, R., Barkham, T., Reif, B., Leipold, E., Roy, S., Misra, A. K., Lakshminarayanan, R., Lee, D. K. & Bhunia, A., 1 Okt. 2022, in: Biochimica et Biophysica Acta - Biomembranes. 1864, 10, 183996.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Structural Insights 100%
  • Fungal Membrane 100%
  • Ergosterol 100%
  • Antifungal Peptide 100%
  • Antimicrobial Peptides 100%
  9 Zitate (Scopus)
• 2021

  Phosphorylation activates the yeast small heat shock protein Hsp26 by weakening domain contacts in the oligomer ensemble

  Mühlhofer, M., Peters, C., Kriehuber, T., Kreuzeder, M., Kazman, P., Rodina, N., Reif, B., Haslbeck, M., Weinkauf, S. & Buchner, J., Dez. 2021, in: Nature Communications. 12, 1, 6697.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Phosphorylation 100%
  • Small Heat Shock Protein (sHSP) 100%
  • Hsp26 100%
  • N-Terminus 100%
  • Heat Shock Protein 100%
  13 Zitate (Scopus)

• Solid state NMR assignments of a human λ-III immunoglobulin light chain amyloid fibril

  Pradhan, T., Annamalai, K., Sarkar, R., Hegenbart, U., Schönland, S., Fändrich, M. & Reif, B., Apr. 2021, in: Biomolecular NMR Assignments. 15, 1, S. 9-16 8 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Solid-state NMR 100%
  • Light Chain 100%
  • Amyloid Fibrils 100%
  • Light Chain Amyloidosis 100%
  • Immunoglobulin Light Chains 100%
  7 Zitate (Scopus)

• Solid-state NMR spectroscopy

  Reif, B., Ashbrook, S. E., Emsley, L. & Hong, M., Dez. 2021, in: Nature Reviews Methods Primers. 1, 1, 2.

  Publikation: Beitrag in Fachzeitschrift › Übersichtsartikel › Begutachtung

  Open Access

  • Solid-state nuclear Magnetic Resonance Spectroscopy 100%
  • Solid-State Nuclear Magnetic Resonance 100%
  • NMR Spectroscopy 100%
  • Nuclear Magnetic Resonance Spectroscopy 100%
  • Nuclear Spin 75%
  225 Zitate (Scopus)
• 2020

  Domain Interactions Determine the Amyloidogenicity of Antibody Light Chain Mutants

  Weber, B., Hora, M., Kazman, P., Pradhan, T., Rührnößl, F., Reif, B. & Buchner, J., 20 Nov. 2020, in: Journal of Molecular Biology. 432, 23, S. 6187-6199 13 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  • Variable Domains 100%
  • Domain-domain Interaction 100%
  • Amyloidogenicity 100%
  • Antibody Light Chain 100%
  • Light Chain 100%
  13 Zitate (Scopus)

• Impact of Magnetic Field Strength on Resolution and Sensitivity of Proton Resonances in Biological Solids

  Xue, K., Sarkar, R., Lalli, D., Koch, B., Pintacuda, G., Tosner, Z. & Reif, B., 15 Okt. 2020, in: Journal of Physical Chemistry C. 124, 41, S. 22631-22637 7 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Proton 100%
  • Magnetic Field Strength 100%
  • Biological Solids 100%
  • Magnetic Field 100%
  • Field Strength 100%
  14 Zitate (Scopus)

• Mapping the Binding Interface of PET Tracer Molecules and Alzheimer Disease Aβ Fibrils by Using MAS Solid-State NMR Spectroscopy

  Niu, Z., Sarkar, R., Aichler, M., Wester, H. J., Yousefi, B. H. & Reif, B., 1 Sept. 2020, in: ChemBioChem. 21, 17, S. 2495-2502 8 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Alzheimer's Disease 100%
  • MAS NMR 100%
  • Binding Interface 100%
  • Solid-state NMR Spectroscopy 100%
  • Positron Emission Tomography Tracers 100%
  12 Zitate (Scopus)

• Seeded fibrils of the germline variant of human l-III immunoglobulin light chain FOR005 have a similar core as patient fibrils with reduced stability

  Pradhan, T., Annamalai, K., Sarkar, R., Huhn, S., Hegenbart, U., Schönland, S., Fändrich, M. & Reif, B., 25 Dez. 2020, in: Journal of Biological Chemistry. 295, 52, S. 18474-18484 11 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Fibril Structure 100%
  • Immunoglobulin Light Chains 100%
  • Germline Variants 100%
  • Germline 100%
  • Light Chain 100%
  16 Zitate (Scopus)

• Small molecule induced toxic human-IAPP species characterized by NMR

  Cox, S. J., Rodriguez Camargo, D. C., Lee, Y. H., Dubini, R. C. A., Rovó, P., Ivanova, M. I., Padmini, V., Reif, B. & Ramamoorthy, A., 7 Nov. 2020, in: Chemical Communications. 56, 86, S. 13129-13132 4 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Small Molecules 100%
  • Human Islet Amyloid Polypeptide (hIAPP) 100%
  • Human IAPP 100%
  • Toxic 100%
  • NMR Spectroscopy 100%
  23 Zitate (Scopus)

• Structural Insight into IAPP-Derived Amyloid Inhibitors and Their Mechanism of Action

  Niu, Z., Prade, E., Malideli, E., Hille, K., Jussupow, A., Mideksa, Y. G., Yan, L. M., Qian, C., Fleisch, M., Messias, A. C., Sarkar, R., Sattler, M., Lamb, D. C., Feige, M. J., Camilloni, C., Kapurniotu, A. & Reif, B., 27 März 2020, in: Angewandte Chemie International Edition in English. 59, 14, S. 5771-5781 11 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • ISM 100%
  • Mechanism of Action 100%
  • Structural Insights 100%
  • Human Islet Amyloid Polypeptide (hIAPP) 100%
  • Amyloid Inhibitor 100%
  18 Zitate (Scopus)
• 2019

  Accessing Methyl Groups in Proteins via ¹H-detected MAS Solid-state NMR Spectroscopy Employing Random Protonation

  Asami, S. & Reif, B., 1 Dez. 2019, in: Scientific Reports. 9, 1, 15903.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Protonation 100%
  • Methyl Groups 100%
  • MAS Solid-state NMR 100%
  • Solid-state NMR Spectroscopy 100%
  • Methyl Group 100%
  15 Zitate (Scopus)

• Accurate Determination of ¹H-¹⁵N Dipolar Couplings Using Inaccurate Settings of the Magic Angle in Solid-State NMR Spectroscopy

  Xue, K., Mühlbauer, M., Mamone, S., Sarkar, R. & Reif, B., 22 März 2019, in: Angewandte Chemie International Edition in English. 58, 13, S. 4286-4290 5 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  • Accurate Determination 100%
  • Dipolar Coupling 100%
  • Magic Angle 100%
  • Solid-state NMR Spectroscopy 100%
  • Magic Angle Spinning 100%
  15 Zitate (Scopus)

• Determination of methyl order parameters using solid state NMR under off magic angle spinning

  Xue, K., Mamone, S., Koch, B., Sarkar, R. & Reif, B., 1 Sept. 2019, in: Journal of Biomolecular NMR. 73, 8-9, S. 471-475 5 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  • Methyl 100%
  • Solid-state NMR 100%
  • Order Parameter 100%
  • Magic Angle Spinning 100%
  • Solid-State NMR 100%
  11 Zitate (Scopus)

• MAS dependent sensitivity of different isotopomers in selectively methyl protonated protein samples in solid state NMR

  Xue, K., Sarkar, R., Tosner, Z., Lalli, D., Motz, C., Koch, B., Pintacuda, G. & Reif, B., 1 Nov. 2019, in: Journal of Biomolecular NMR. 73, 10-11, S. 625-631 7 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Methyl 100%
  • Solid-state NMR 100%
  • Isotopomers 100%
  • Protein Sample 100%
  • CHD2 100%
  14 Zitate (Scopus)

• Probing transient non-native states in amyloid beta fiber elongation by NMR

  Brender, J. R., Ghosh, A., Kotler, S. A., Krishnamoorthy, J., Bera, S., Morris, V., Sil, T. B., Garai, K., Reif, B., Bhunia, A. & Ramamoorthy, A., 2019, in: Chemical Communications. 55, 31, S. 4483-4486 4 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Non-native States 100%
  • Degree of Interaction 100%
  • Amyloid beta 100%
  • Fiber Elongation 100%
  • Conformation 100%
  44 Zitate (Scopus)

• The structure and oxidation of the eye lens chaperone αA-crystallin

  Kaiser, C. J. O., Peters, C., Schmid, P. W. N., Stavropoulou, M., Zou, J., Dahiya, V., Mymrikov, E. V., Rockel, B., Asami, S., Haslbeck, M., Rappsilber, J., Reif, B., Zacharias, M., Buchner, J. & Weinkauf, S., 1 Dez. 2019, in: Nature Structural and Molecular Biology. 26, 12, S. 1141-1150 10 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Crystallin 100%
  • Chaperone 100%
  • Eye Lens 100%
  • Disulfide 28%
  • NMR Spectroscopy 14%
  44 Zitate (Scopus)
• 2018

  A single residue switch reveals principles of antibody domain integrity

  Weber, B., Brandl, M. J., Cendales, M. D. P., Berner, C., Pradhan, T., Feind, G. M., Zacharias, M., Reif, B. & Buchner, J., 2018, in: Journal of Biological Chemistry. 293, 44, S. 17107-17118 12 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Helix 100%
  • Antibody Domain 100%
  • C-Terminus 100%
  • Melting Temperature 66%
  • CH2 Domain 66%
  8 Zitate (Scopus)

• Epigallocatechin gallate (EGCG) reduces the intensity of pancreatic amyloid fibrils in human islet amyloid polypeptide (hIAPP) transgenic mice

  Franko, A., Rodriguez Camargo, D. C., Böddrich, A., Garg, D., Rodriguez Camargo, A., Rathkolb, B., Janik, D., Aichler, M., Feuchtinger, A., Neff, F., Fuchs, H., Wanker, E. E., Reif, B., Häring, H. U., Peter, A. & Hrabě De Angelis, M., 1 Dez. 2018, in: Scientific Reports. 8, 1, 1116.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Transgenic Mice 100%
  • Epigallocatechin Gallate 100%
  • Amyloid Fibrils 100%
  • Human Islet Amyloid Polypeptide (hIAPP) 100%
  • Transgenic Mouse 100%
  48 Zitate (Scopus)

• HIAPP forms toxic oligomers in plasma

  Rodriguez Camargo, D. C., Garg, D., Buday, K., Franko, A., Rodriguez Camargo, A., Schmidt, F., Cox, S. J., Suladze, S., Haslbeck, M., Mideksa, Y. G., Gemmecker, G., Aichler, M., Mettenleiter, G., Schulz, M., Walch, A. K., Hrabě De Angelis, M., Feige, M. J., Sierra, C. A., Conrad, M. & Tripsianes, K. &2 mehr, Ramamoorthy, A. & Reif, B., 2018, in: Chemical Communications. 54, 43, S. 5426-5429 4 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Human Islet Amyloid Polypeptide (hIAPP) 100%
  • Toxic Oligomers 100%
  • Blood Plasma 100%
  • Glucose Blood Level 50%
  • Cytotoxicity 50%
  30 Zitate (Scopus)

• Magic-Angle Spinning Frequencies beyond 300 kHz Are Necessary to Yield Maximum Sensitivity in Selectively Methyl Protonated Protein Samples in Solid-State NMR

  Xue, K., Sarkar, R., Motz, C., Asami, S., Decker, V., Wegner, S., Tosner, Z. & Reif, B., 19 Juli 2018, in: Journal of Physical Chemistry C. 122, 28, S. 16437-16442 6 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  • Methyl 100%
  • Solid-state NMR 100%
  • Maximum Sensitivity 100%
  • Protein Sample 100%
  • Magic Angle Spinning 100%
  32 Zitate (Scopus)

• Overcoming Volume Selectivity of Dipolar Recoupling in Biological Solid-State NMR Spectroscopy

  Tošner, Z., Sarkar, R., Becker-Baldus, J., Glaubitz, C., Wegner, S., Engelke, F., Glaser, S. J. & Reif, B., 26 Okt. 2018, in: Angewandte Chemie International Edition in English. 57, 44, S. 14514-14518 5 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  • Solid-state NMR Spectroscopy 100%
  • Biological Solids 100%
  • Dipolar Recoupling 100%
  • Solid-State NMR 100%
  • NMR Spectroscopy 100%
  35 Zitate (Scopus)

• Physical basis of amyloid fibril polymorphism

  Close, W., Neumann, M., Schmidt, A., Hora, M., Annamalai, K., Schmidt, M., Reif, B., Schmidt, V., Grigorieff, N. & Fändrich, M., 1 Dez. 2018, in: Nature Communications. 9, 1, 699.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Amyloid Fibrils 100%
  • Fibril Polymorphism 100%
  • Fibril Morphology 100%
  • Amyloid Protein 100%
  • Amyloid Fibril 100%
  129 Zitate (Scopus)

• Proton-detection in biological MAS solid-state NMR spectroscopy

  Reif, B., 13 Juni 2018, Modern Magnetic Resonance. Springer International Publishing, S. 879-910 32 S.

  Publikation: Beitrag in Buch/Bericht/Konferenzband › Kapitel › Begutachtung

  • MAS Solid-state NMR 100%
  • Solid-state NMR Spectroscopy 100%
  • Proton Detection 100%
  • Nuclear Magnetic Resonance Spectroscopy 100%
  • Linewidth 100%
  1 Zitat (Scopus)

• Reconstitution of isotopically labeled ribosomal protein L29 in the 50S large ribosomal subunit for solution-state and solid-state NMR

  Barbet-Massin, E., van der Sluis, E., Musial, J., Beckmann, R. & Reif, B., 2018, Methods in Molecular Biology. Humana Press Inc., S. 87-100 14 S. (Methods in Molecular Biology; Band 1764).

  Publikation: Beitrag in Buch/Bericht/Konferenzband › Kapitel › Begutachtung

  • Solution State 100%
  • Solid-state nuclear Magnetic Resonance (ssNMR) 100%
  • Reconstitution 100%
  • Ribosomal Protein 100%
  • Isotopically Labeled 100%
  6 Zitate (Scopus)

• The Antibody Light-Chain Linker Regulates Domain Orientation and Amyloidogenicity

  Weber, B., Hora, M., Kazman, P., Göbl, C., Camilloni, C., Reif, B. & Buchner, J., 7 Dez. 2018, in: Journal of Molecular Biology. 430, 24, S. 4925-4940 16 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  • Linker 100%
  • Domain Orientation 100%
  • Light Chain 100%
  • Amyloidogenicity 100%
  • Antibody Light Chain 100%
  25 Zitate (Scopus)

• The neuronal S100B protein is a calcium-tuned suppressor of amyloid- aggregation

  Cristóvão, J. S., Morris, V. K., Cardoso, I., Leal, S. S., Martínez, J., Botelho, H. M., Göbl, C., David, R., Kierdorf, K., Alemi, M., Madl, T., Fritz, G., Reif, B. & Gomes, C. M., 29 Juni 2018, in: Science Advances. 4, 6, eaaq1702.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Protein S100B 100%
  • Amyloid Protein 100%
  • Alzheimer's Disease 100%
  • S100B 100%
  • S100 Proteins 100%
  45 Zitate (Scopus)
• 2017

  Comparative Study of REDOR and CPPI Derived Order Parameters by ¹H-Detected MAS NMR and MD Simulations

  Asami, S. & Reif, B., 21 Sept. 2017, in: Journal of Physical Chemistry B. 121, 37, S. 8719-8730 12 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  • Experimental Result 100%
  • Reference Value 100%
  • Observables 100%
  • Systematic Error 100%
  • Dynamic Property 100%
  22 Zitate (Scopus)

• Limits of Resolution and Sensitivity of Proton Detected MAS Solid-State NMR Experiments at 111 kHz in Deuterated and Protonated Proteins

  Xue, K., Sarkar, R., Motz, C., Asami, S., Camargo, D. C. R., Decker, V., Wegner, S., Tosner, Z. & Reif, B., 1 Dez. 2017, in: Scientific Reports. 7, 1, 7444.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Proton 100%
  • NMR Experiments 100%
  • Resolution Limit 100%
  • Deuteration 100%
  • MAS Solid-state NMR 100%
  39 Zitate (Scopus)

• MAK33 antibody light chain amyloid fibrils are similar to oligomeric precursors

  Hora, M., Sarkar, R., Morris, V., Xue, K., Prade, E., Harding, E., Buchner, J. & Reif, B., Juli 2017, in: PLoS ONE. 12, 7, e0181799.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • NMR Studies 100%
  • Oligomeric 100%
  • Fibril Formation 100%
  • Amyloid Fibrils 100%
  • Light Chain Amyloidosis 100%
  25 Zitate (Scopus)

• Radiofrequency fields in MAS solid state NMR probes

  Tošner, Z., Purea, A., Struppe, J. O., Wegner, S., Engelke, F., Glaser, S. J. & Reif, B., Nov. 2017, in: Journal of Magnetic Resonance. 284, S. 20-32 13 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  • Radio Frequency 100%
  • Radiofrequency Fields 100%
  • MAS NMR 100%
  • Solid-state NMR Probe 100%
  • Rotors 100%
  34 Zitate (Scopus)

• Solid- and solution-state nuclear magnetic resonance spectroscopic studies on antibody light chain amyloid formation and interactions with epigallocatechin gallate

  Hora, M., Carballo Pacheco, M., Weber, B., Buchner, J., Strodel, B. & Reif, B., 16 März 2017, in: Amyloid. 24, S. 10 1 S.

  Publikation: Beitrag in Fachzeitschrift › Brief › Begutachtung

• Stabilization and structural analysis of a membrane-associated hIAPP aggregation intermediate

  Rodriguez Camargo, D. C., Korshavn, K. J., Jussupow, A., Raltchev, K., Goricanec, D., Fleisch, M., Sarkar, R., Xue, K., Aichler, M., Mettenleiter, G., Walch, A. K., Camilloni, C., Hagn, F., Reif, B. & Ramamoorthy, A., 17 Nov. 2017, in: eLife. 6, e31226.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Membrane-associated 100%
  • Human Islet Amyloid Polypeptide (hIAPP) 100%
  • Aggregation Intermediates 100%
  • Nanodisc 100%
  • formation 100%
  67 Zitate (Scopus)

• The redox environment triggers conformational changes and aggregation of hIAPP in Type II Diabetes

  Rodriguez Camargo, D. C., Tripsianes, K., Buday, K., Franko, A., Göbl, C., Hartlmüller, C., Sarkar, R., Aichler, M., Mettenleiter, G., Schulz, M., Böddrich, A., Erck, C., Martens, H., Walch, A. K., Madl, T., Wanker, E. E., Conrad, M., De Angelis, M. H. & Reif, B., 13 März 2017, in: Scientific Reports. 7, 44041.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Type 2 Diabetes Mellitus (T2DM) 100%
  • Conformational Change 100%
  • Human Islet Amyloid Polypeptide (hIAPP) 100%
  • Redox Environment 100%
  • Amylin 100%
  75 Zitate (Scopus)
• 2016

  A Stable Mutant Predisposes Antibody Domains to Amyloid Formation through Specific Non-Native Interactions

  Nokwe, C. N., Hora, M., Zacharias, M., Yagi, H., Peschek, J., Reif, B., Goto, Y. & Buchner, J., 27 März 2016, in: Journal of Molecular Biology. 428, 6, S. 1315-1332 18 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  • Variable Domains 100%
  • Antibody Domain 100%
  • Amyloid Formation 100%
  • Native Interaction 100%
  • Stable mutants 100%
  19 Zitate (Scopus)

• Immobilization of soluble protein complexes in MAS solid-state NMR: Sedimentation versus viscosity

  Sarkar, R., Mainz, A., Busi, B., Barbet-Massin, E., Kranz, M., Hofmann, T. & Reif, B., 1 Juni 2016, in: Solid State Nuclear Magnetic Resonance. 76-77, S. 7-14 8 S.

  Publikation: Beitrag in Fachzeitschrift › Übersichtsartikel › Begutachtung

  • Immobilization 100%
  • Viscosity 100%
  • Soluble Complexes 100%
  • MAS Solid-state NMR 100%
  • Solid-State NMR 100%
  10 Zitate (Scopus)

• Sulindac Sulfide Induces the Formation of Large Oligomeric Aggregates of the Alzheimer's Disease Amyloid-β Peptide Which Exhibit Reduced Neurotoxicity

  Prade, E., Barucker, C., Sarkar, R., Althoff-Ospelt, G., Lopez Del Amo, J. M., Hossain, S., Zhong, Y., Multhaup, G. & Reif, B., 29 März 2016, in: Biochemistry. 55, 12, S. 1839-1849 11 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  • Alzheimer's Disease 100%
  • Neurotoxicity 100%
  • Oligomeric Aggregates 100%
  • Amyloid-β Peptide 100%
  • Sulindac Sulfide 100%
  41 Zitate (Scopus)
• 2015

  Access to Cα backbone dynamics of biological solids by¹³C T₁ Relaxation and molecular dynamics simulation

  Asami, S., Porter, J. R., Lange, O. F. & Reif, B., 28 Jan. 2015, in: Journal of the American Chemical Society. 137, 3, S. 1094-1100 7 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  • Proton 100%
  • Aliphatic Carbon 100%
  • Parameter Extraction 100%
  • Deuteration 100%
  • Molecular Dynamics Simulation 100%
  31 Zitate (Scopus)

• A Hot-Segment-Based Approach for the Design of Cross-Amyloid Interaction Surface Mimics as Inhibitors of Amyloid Self-Assembly

  Andreetto, E., Malideli, E., Yan, L. M., Kracklauer, M., Farbiarz, K., Tatarek-Nossol, M., Rammes, G., Prade, E., Neumüller, T., Caporale, A., Spanopoulou, A., Bakou, M., Reif, B. & Kapurniotu, A., 1 Okt. 2015, in: Angewandte Chemie International Edition in English. 54, 44, S. 13095-13100 6 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  • Segmentation Approach 100%
  • Interaction Surface 100%
  • Self-assembly 100%
  • Amyloid Protein 100%
  • Amylin 60%
  50 Zitate (Scopus)

• Cloning, expression and purification of the human Islet Amyloid Polypeptide (hIAPP) from Escherichia coli

  Rodriguez Camargo, D. C., Tripsianes, K., Kapp, T. G., Mendes, J., Schubert, J., Cordes, B. & Reif, B., Feb. 2015, in: Protein Expression and Purification. 106, S. 49-56 8 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  • Escherichia Coli 100%
  • Cloning Expression 100%
  • Human Islet Amyloid Polypeptide (hIAPP) 100%
  • Chitin Binding 100%
  • Escherichia coli 100%
  16 Zitate (Scopus)

• Perspectives for sensitivity enhancement in proton-detected solid-state NMR of highly deuterated proteins by preserving water magnetization

  Chevelkov, V., Xiang, S., Giller, K., Becker, S., Lange, A. & Reif, B., Feb. 2015, in: Journal of Biomolecular NMR. 61, 2, S. 151-160 10 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Proton 100%
  • Solid-state NMR 100%
  • Magnetization 100%
  • Sensitivity Enhancement 100%
  • Deuterated Protein 100%
  9 Zitate (Scopus)

• Restoring Resolution in Biological Solid-State NMR under Conditions of Off-Magic-Angle Spinning

  Sarkar, R., Rodriguez Camargo, D. C., Pintacuda, G. & Reif, B., 1 Dez. 2015, in: Journal of Physical Chemistry Letters. 6, 24, S. 5040-5044 5 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  • Solid-state NMR 100%
  • Magic Angle 100%
  • Biological Solids 100%
  • Magic Angle Spinning 100%
  • Nuclear Magnetic Resonance 100%
  11 Zitate (Scopus)

• Site-specific solid-state NMR studies of "trigger factor" in complex with the large ribosomal subunit 50S

  Barbet-Massin, E., Huang, C. T., Daebel, V., Hsu, S. T. D. & Reif, B., 27 März 2015, in: Angewandte Chemie International Edition in English. 54, 14, S. 4367-4369 3 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  • NMR Studies 100%
  • Solid-state NMR 100%
  • Trigger Factor 100%
  • Ribosome Binding 100%
  • Large Ribosomal Subunit 100%
  35 Zitate (Scopus)

• Structural mechanism of the interaction of Alzheimer disease Aβ fibrils with the non-steroidal anti-inflammatory drug (NSAID) sulindac sulfide

  Prade, E., Bittner, H. J., Sarkar, R., Del Amo, J. M. L., Althoff-Ospelt, G., Multhaup, G., Hildebrand, P. W. & Reif, B., 27 Nov. 2015, in: Journal of Biological Chemistry. 290, 48, S. 28737-28745 9 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  Open Access

  • Alzheimer's Disease 100%
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs) 100%
  • Structural Mechanism 100%
  • Sulindac Sulfide 100%
  • Non-Steroidal Anti-Inflammatory Drug 100%
  27 Zitate (Scopus)

• The Antibody Light-Chain Linker Is Important for Domain Stability and Amyloid Formation

  Nokwe, C. N., Hora, M., Zacharias, M., Yagi, H., John, C., Reif, B., Goto, Y. & Buchner, J., 2015, in: Journal of Molecular Biology. 427, 22, S. 3572-3586 15 S.

  Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

  • Linker 100%
  • Light Chain 100%
  • Amyloid Formation 100%
  • Antibody Light Chain 100%
  • Domain Stability 100%
  21 Zitate (Scopus)